Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1424727..1425234 Replicon chromosome
Accession NZ_CP087952
Organism Desulfosarcina sp. BuS5

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag BuS5_RS07100 Protein ID WP_027354372.1
Coordinates 1424727..1424987 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BuS5_RS07105 Protein ID WP_027354371.1
Coordinates 1424980..1425234 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BuS5_RS07075 (BuS5_01444) 1419904..1420224 - 321 WP_027353189.1 hypothetical protein -
BuS5_RS07080 (BuS5_01445) 1420980..1422353 + 1374 WP_036019348.1 group II intron reverse transcriptase/maturase -
BuS5_RS07085 (BuS5_01447) 1422606..1422980 - 375 WP_027354376.1 hypothetical protein -
BuS5_RS07090 (BuS5_01448) 1423089..1423367 - 279 WP_157487425.1 hypothetical protein -
BuS5_RS07095 1424300..1424593 - 294 WP_027354373.1 hypothetical protein -
BuS5_RS07100 (BuS5_01449) 1424727..1424987 - 261 WP_027354372.1 Txe/YoeB family addiction module toxin Toxin
BuS5_RS07105 (BuS5_01450) 1424980..1425234 - 255 WP_027354371.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BuS5_RS07110 1425982..1426269 + 288 WP_198012277.1 hypothetical protein -
BuS5_RS07115 (BuS5_01451) 1426272..1426538 + 267 WP_274428121.1 AAA family ATPase -
BuS5_RS07120 (BuS5_01452) 1426490..1426819 + 330 WP_084446082.1 hypothetical protein -
BuS5_RS07125 (BuS5_01453) 1427003..1428307 + 1305 WP_232223083.1 Xaa-Pro peptidase family protein -
BuS5_RS07130 (BuS5_01454) 1428501..1429922 + 1422 WP_084446077.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10367.80 Da        Isoelectric Point: 9.4404

>T226482 WP_027354372.1 NZ_CP087952:c1424987-1424727 [Desulfosarcina sp. BuS5]
MSRILAWTDEAWQGYLYWQSQDRKTLKRINKLIEDTKREPFVGIGKPEPLRENLSGFWSRRIDDTNRLVYAVNDNFIAII
SCRYHY

Download         Length: 261 bp

>T226482 NZ_CP122499:c773111-772734 [Escherichia coli]
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGTTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCAGGATTC
AGCGCCTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9633.85 Da        Isoelectric Point: 5.6725

>AT226482 WP_027354371.1 NZ_CP087952:c1425234-1424980 [Desulfosarcina sp. BuS5]
MRVVNFSEARNNLKSVLDQVVDDANYTIITRRDSENAVVMSLDTFNSYMETFHLLRSPANAAHLSKSIEQYKNGKVQEKE
LIVE

Download         Length: 255 bp

>AT226482 NZ_CP122499:c773532-773158 [Escherichia coli]
GTGTCAGACACTCTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References