Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4646616..4647394 Replicon chromosome
Accession NZ_CP087880
Organism Pseudocitrobacter corydidari isolate G163CM

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag G163CM_RS21720 Protein ID WP_231826254.1
Coordinates 4646906..4647394 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag G163CM_RS21715 Protein ID WP_231826253.1
Coordinates 4646616..4646909 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G163CM_RS21715 (4646616) 4646616..4646909 + 294 WP_231826253.1 DUF1778 domain-containing protein Antitoxin
G163CM_RS21720 (4646906) 4646906..4647394 + 489 WP_231826254.1 GNAT family N-acetyltransferase Toxin
G163CM_RS21725 (4648096) 4648096..4648560 - 465 WP_231826255.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(78-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17508.44 Da        Isoelectric Point: 7.7297

>T226468 WP_231826254.1 NZ_CP087880:4646906-4647394 [Pseudocitrobacter corydidari]
MISAPEPLHAGHVLTSFCCGVDSMDNWLKQRAMKNQITGASRTFVCCDTTKVMAYYSLASSAVMTNTAPGRFSRNMPDPI
PVVVLGRLAVDVSRHGQGIGRALVRDAGLRVIQVAETIGIRGMLVHALSDEARESYLRVGFEPSPIDPMMLMVTLGDLSM
IA

Download         Length: 489 bp

>T226468 NZ_CP122496:2509121-2509228 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10901.44 Da        Isoelectric Point: 8.6351

>AT226468 WP_231826253.1 NZ_CP087880:4646616-4646909 [Pseudocitrobacter corydidari]
MPAANSLSIKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQAFLTRLDQAPAPN
DALRKTMQTAAPWEQEK

Download         Length: 294 bp

>AT226468 NZ_CP122496:c2509074-2509008 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References