Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 4175043..4175852 Replicon chromosome
Accession NZ_CP087880
Organism Pseudocitrobacter corydidari isolate G163CM

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag G163CM_RS19360 Protein ID WP_231826006.1
Coordinates 4175316..4175852 (+) Length 179 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag G163CM_RS19355 Protein ID WP_015962628.1
Coordinates 4175043..4175312 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G163CM_RS19335 (4170637) 4170637..4171305 + 669 WP_015962623.1 cell division ATP-binding protein FtsE -
G163CM_RS19340 (4171298) 4171298..4172353 + 1056 WP_015962624.1 permease-like cell division protein FtsX -
G163CM_RS19345 (4172597) 4172597..4173451 + 855 WP_015962625.1 RNA polymerase sigma factor RpoH -
G163CM_RS19350 (4173790) 4173790..4174893 + 1104 WP_041686153.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
G163CM_RS19355 (4175043) 4175043..4175312 + 270 WP_015962628.1 DUF1778 domain-containing protein Antitoxin
G163CM_RS19360 (4175316) 4175316..4175852 + 537 WP_231826006.1 GNAT family N-acetyltransferase Toxin
G163CM_RS19365 (4175818) 4175818..4176201 - 384 WP_149464105.1 aspartate 1-decarboxylase autocleavage activator PanM -
G163CM_RS19370 (4176622) 4176622..4177731 + 1110 WP_015962631.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
G163CM_RS19375 (4177786) 4177786..4178712 + 927 WP_149464107.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
G163CM_RS19380 (4178709) 4178709..4179986 + 1278 WP_015962633.1 high-affinity branched-chain amino acid ABC transporter permease LivM -
G163CM_RS19385 (4179983) 4179983..4180750 + 768 WP_015962634.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(82-147)

Antitoxin

Vibrio phage ICP1, Orf50

(8-84)


Sequences

Toxin        


Download         Length: 179 a.a.        Molecular weight: 20137.13 Da        Isoelectric Point: 8.8964

>T226466 WP_231826006.1 NZ_CP087880:4175316-4175852 [Pseudocitrobacter corydidari]
VQDLIIEILQDDVEYDWRQFDCGEASLNLFLKEHLRRQHDGKVLRGYVLRNRNVVLGYYTLSGSCFERLALPSKSGQKKI
PYQNIPSVTLGRLAVDKSLQGEGWGSLLVTHAMKVVYQASQAVGIYGLFVEALNDKAHAFYLSLGFIPLVRENRRALFYP
TQSIERLFTASPTHPPAP

Download         Length: 537 bp

>T226466 NZ_CP122496:1913475-1913578 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10219.68 Da        Isoelectric Point: 5.2065

>AT226466 WP_015962628.1 NZ_CP087880:4175043-4175312 [Pseudocitrobacter corydidari]
MPALKKQRIDLRLSDDDKSMIEEAAAITNQSVTQFMLNSASERAAAVIEEHRRIVLNEDSWKRVMDALDTPPEPNEKLKR
AARRLLDME

Download         Length: 270 bp

>AT226466 NZ_CP122496:c1913616-1913345 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References