Detailed information of TA system TA226451

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): chpSB/PRK09812-ChpS
• Location: 3300892..3301487
• Replicon: chromosome
• Accession: NZ_CP087880
• Organism: Pseudocitrobacter corydidari isolate G163CM

Toxin (Protein)

• Gene name: chpB
• Uniprot ID: -
• Locus tag: G163CM_RS15390
• Protein ID: WP_015966164.1
• Coordinates: 3300892..3301242 (-)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: chpS
• Uniprot ID: -
• Locus tag: G163CM_RS15395
• Protein ID: WP_231825547.1
• Coordinates: 3301236..3301487 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G163CM_RS15370 (3296274)	3296274..3297299	-	1026	WP_231825544.1	ABC transporter permease	-
G163CM_RS15375 (3297310)	3297310..3298812	-	1503	WP_231825545.1	sugar ABC transporter ATP-binding protein	-
G163CM_RS15380 (3298907)	3298907..3299863	-	957	WP_231825546.1	ABC transporter substrate-binding protein	-
G163CM_RS15385 (3300256)	3300256..3300783	+	528	WP_004857176.1	inorganic diphosphatase	-
G163CM_RS15390 (3300892)	3300892..3301242	-	351	WP_015966164.1	type II toxin-antitoxin system ChpB family toxin	Toxin
G163CM_RS15395 (3301236)	3301236..3301487	-	252	WP_231825547.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
G163CM_RS15400 (3301695)	3301695..3302039	-	345	WP_015966166.1	gamma-glutamylcyclotransferase	-
G163CM_RS15405 (3302042)	3302042..3305821	-	3780	WP_231825548.1	autotransporter assembly complex protein TamB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (9-111)

Antitoxin

• SpoVT-AbrB domain (6-50)

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 12222.22 Da
• Isoelectric Point: 9.1446

>T226451 WP_015966164.1 NZ_CP087880:c3301242-3300892 [Pseudocitrobacter corydidari]
MVKSPMFARGDIVLVGFDPASGHEQKGEGRPALVLSVSAFNRLGMVLVAPVTRGGNHARYAGFAVPLSCKTGDVSGVVLV
NQFRMMDLNARGAKKLGEASAEVVEDVLLRAQAILD

Nucleotide

• Length: 351 bp

>T226451 NZ_CP122492:c4434007-4433834 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9210.59 Da
• Isoelectric Point: 4.9777

>AT226451 WP_231825547.1 NZ_CP087880:c3301487-3301236 [Pseudocitrobacter corydidari]
MHVTIKKWGNSMGMVIPGTVVKELNLSAGQNMEVEVKEHQIILTPLKRHYSLDALLAQCDINAPALSEQELWGQSGPQGD
EVW

Nucleotide

• Length: 252 bp

>AT226451 NZ_CP122492:c4434331-4434035 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CTTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG