Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3279835..3280357 Replicon chromosome
Accession NZ_CP087880
Organism Pseudocitrobacter corydidari isolate G163CM

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G163CM_RS15275 Protein ID WP_231825536.1
Coordinates 3279835..3280125 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G163CM_RS15280 Protein ID WP_231825537.1
Coordinates 3280115..3280357 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G163CM_RS15260 (3275099) 3275099..3276754 + 1656 WP_231825533.1 alpha,alpha-phosphotrehalase -
G163CM_RS15265 (3277137) 3277137..3279275 + 2139 WP_231825534.1 anaerobic ribonucleoside-triphosphate reductase -
G163CM_RS15270 (3279374) 3279374..3279838 + 465 WP_231825535.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
G163CM_RS15275 (3279835) 3279835..3280125 - 291 WP_231825536.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G163CM_RS15280 (3280115) 3280115..3280357 - 243 WP_231825537.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
G163CM_RS15285 (3280435) 3280435..3282348 - 1914 WP_231825538.1 PRD domain-containing protein -
G163CM_RS15290 (3282369) 3282369..3283520 - 1152 WP_231825539.1 lactonase family protein -
G163CM_RS15295 (3283617) 3283617..3284357 - 741 WP_015966145.1 KDGP aldolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-65)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11251.20 Da        Isoelectric Point: 10.2491

>T226450 WP_231825536.1 NZ_CP087880:c3280125-3279835 [Pseudocitrobacter corydidari]
MIYELAFDPRALKEWQKLGATVREQFKKKLKVVLLHPRNEADRLRTFPDCYKIKLKASGFRLVYQVQEAQVTVLVIAIGK
REKSAVYQDADKRLED

Download         Length: 291 bp

>T226450 NZ_CP122492:c4337688-4337338 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9048.43 Da        Isoelectric Point: 5.0916

>AT226450 WP_231825537.1 NZ_CP087880:c3280357-3280115 [Pseudocitrobacter corydidari]
MATINVRLDDQLKKEAYAVLEKLNITPTEAVRLLFQYLADNGRMPVKNVTISDSEEALLHSVRERLAAPQEAVKVRLDDL

Download         Length: 243 bp

>AT226450 NZ_CP122492:c4337933-4337682 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCTTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGCGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References