Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 1239104..1239846 Replicon chromosome
Accession NZ_CP087880
Organism Pseudocitrobacter corydidari isolate G163CM

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag G163CM_RS05790 Protein ID WP_231827205.1
Coordinates 1239367..1239846 (+) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag G163CM_RS05785 Protein ID WP_015964343.1
Coordinates 1239104..1239373 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G163CM_RS05765 (1235429) 1235429..1236625 - 1197 WP_231827201.1 mandelate racemase/muconate lactonizing enzyme family protein -
G163CM_RS05770 (1236941) 1236941..1237945 + 1005 WP_231827202.1 LacI family DNA-binding transcriptional regulator -
G163CM_RS05775 (1238012) 1238012..1238629 + 618 WP_231827203.1 glutathione S-transferase family protein -
G163CM_RS05780 (1238724) 1238724..1239011 + 288 WP_231827204.1 hypothetical protein -
G163CM_RS05785 (1239104) 1239104..1239373 + 270 WP_015964343.1 DUF1778 domain-containing protein Antitoxin
G163CM_RS05790 (1239367) 1239367..1239846 + 480 WP_231827205.1 GNAT family N-acetyltransferase Toxin
G163CM_RS05795 (1239915) 1239915..1240142 + 228 WP_015964345.1 tautomerase PptA -
G163CM_RS05800 (1240188) 1240188..1240760 - 573 WP_231827206.1 flavin reductase family protein -
G163CM_RS05805 (1240954) 1240954..1241730 + 777 WP_231827207.1 MBL fold metallo-hydrolase -
G163CM_RS05810 (1241815) 1241815..1242660 + 846 WP_015964347.1 N-hydroxyarylamine O-acetyltransferase -
G163CM_RS05815 (1242664) 1242664..1243620 - 957 WP_231827208.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(54-145)

Antitoxin

Vibrio phage ICP1, Orf50

(10-84)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17675.51 Da        Isoelectric Point: 9.8831

>T226443 WP_231827205.1 NZ_CP087880:1239367-1239846 [Pseudocitrobacter corydidari]
MVKDLTERLTYSHNVDEFSCGEPVLDNWLRSRALSNEESGATRTFVLCPKGSQQVIGYYSLSTGAIQREAVPGAFRRNMP
EPIPVVLIARFAVDSAFQKQRWGGKLLREAVMRAMLIAETVGVRGLVVHALNDAAKAFYLRFGFVVSPIQPHTLVLALR

Download         Length: 480 bp

>T226443 NZ_CP122492:1992982-1993085 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10392.79 Da        Isoelectric Point: 4.5741

>AT226443 WP_015964343.1 NZ_CP087880:1239104-1239373 [Pseudocitrobacter corydidari]
MTSRNKEAPINLRANQRQRDLIDLAAQLISLSRTDFMLNAACEKAQEVLLDQRLFIVDDQQFAEFQRILDTPLSENKGFQ
ELMSDKYSW

Download         Length: 270 bp

>AT226443 NZ_CP122492:c1993123-1992852 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGTAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References