Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1797000..1797577 Replicon chromosome
Accession NZ_CP087865
Organism Moraxella bovis strain SAM57868

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP122_RS08680 Protein ID WP_078275234.1
Coordinates 1797000..1797335 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP122_RS08685 Protein ID WP_078275235.1
Coordinates 1797335..1797577 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP122_RS08660 (LP122_08575) 1792700..1793284 + 585 WP_264684517.1 hypothetical protein -
LP122_RS08665 (LP122_08580) 1793449..1795593 + 2145 WP_264678021.1 cation-translocating P-type ATPase -
LP122_RS08670 (LP122_08585) 1795683..1795919 - 237 WP_264678020.1 hypothetical protein -
LP122_RS08675 (LP122_08590) 1795943..1796938 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP122_RS08680 (LP122_08595) 1797000..1797335 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP122_RS08685 (LP122_08600) 1797335..1797577 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP122_RS08690 (LP122_08605) 1797784..1798863 + 1080 WP_264678019.1 3-deoxy-7-phosphoheptulonate synthase -
LP122_RS08695 (LP122_08610) 1799203..1799815 + 613 Protein_1688 IS607 family transposase -
LP122_RS08700 (LP122_08615) 1799899..1800031 + 133 Protein_1689 transposase -
LP122_RS08705 (LP122_08620) 1800028..1800987 + 960 WP_264683651.1 transposase -
LP122_RS08710 (LP122_08625) 1801235..1801957 - 723 WP_264678018.1 tRNA pseudouridine(65) synthase TruC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226431 WP_078275234.1 NZ_CP087865:c1797335-1797000 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226431 NZ_CP122492:193090-193197 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGTATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226431 WP_078275235.1 NZ_CP087865:c1797577-1797335 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226431 NZ_CP122492:c193032-192976 [Escherichia coli]
CAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References