Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1167322..1167811 Replicon chromosome
Accession NZ_CP087865
Organism Moraxella bovis strain SAM57868

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP122_RS05615 Protein ID WP_264676856.1
Coordinates 1167554..1167811 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP122_RS05610 Protein ID WP_228157840.1
Coordinates 1167322..1167564 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP122_RS05570 (LP122_05525) 1162412..1163461 + 1050 WP_264676261.1 RluA family pseudouridine synthase -
LP122_RS05575 (LP122_05530) 1163580..1164377 + 798 WP_264676861.1 polyphenol oxidase family protein -
LP122_RS05580 1164374..1164586 + 213 WP_264676860.1 bestrophin family protein -
LP122_RS05585 (LP122_05535) 1164576..1164983 + 408 WP_264676859.1 bestrophin family protein -
LP122_RS05590 1165264..1165787 + 524 Protein_1077 DUF853 family protein -
LP122_RS05595 (LP122_05540) 1165774..1166721 + 948 WP_264676857.1 DUF853 domain-containing protein -
LP122_RS05600 (LP122_05545) 1166744..1167031 + 288 WP_115005096.1 DUF1315 family protein -
LP122_RS05605 (LP122_05550) 1167113..1167277 - 165 WP_158079593.1 hypothetical protein -
LP122_RS05610 (LP122_05555) 1167322..1167564 + 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP122_RS05615 (LP122_05560) 1167554..1167811 + 258 WP_264676856.1 Txe/YoeB family addiction module toxin Toxin
LP122_RS05620 (LP122_05565) 1167870..1168379 + 510 WP_264676855.1 peptidylprolyl isomerase -
LP122_RS05625 (LP122_05570) 1168446..1169249 + 804 WP_264676854.1 UDP-2,3-diacylglucosamine diphosphatase -
LP122_RS05630 (LP122_05575) 1169346..1171832 - 2487 WP_264684011.1 alpha/beta hydrolase -
LP122_RS05635 (LP122_05580) 1171935..1172783 - 849 WP_264676852.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.00 Da        Isoelectric Point: 8.1158

>T226429 WP_264676856.1 NZ_CP087865:1167554-1167811 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRINDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226429 NZ_CP122470:63226-63531 [Klebsiella pneumoniae subsp. pneumoniae]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTTTCCCGTGAACTCTATCCGGTGG
TGCACATCGGGGACGACAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACGTCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226429 WP_228157840.1 NZ_CP087865:1167322-1167564 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226429 NZ_CP122470:63006-63224 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAAGCAGCGCATCACCGTCACCATAGACAGCGACAGTTATCAGTTACTGAAATCCGCGGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTGCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGCTTTATTGATATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References