Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 357707..358265 Replicon chromosome
Accession NZ_CP087865
Organism Moraxella bovis strain SAM57868

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP122_RS01625 Protein ID WP_228157760.1
Coordinates 357993..358265 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP122_RS01620 Protein ID WP_264677330.1
Coordinates 357707..358000 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP122_RS01595 (LP122_01570) 353423..354727 - 1305 WP_264677332.1 valine--pyruvate transaminase -
LP122_RS01600 (LP122_01575) 354848..355459 + 612 WP_115368690.1 methyltransferase -
LP122_RS01605 (LP122_01580) 355566..355916 + 351 WP_181879486.1 PIN domain protein -
LP122_RS01610 (LP122_01585) 355906..356109 + 204 WP_115368689.1 hypothetical protein -
LP122_RS01615 (LP122_01590) 356229..357563 + 1335 WP_264677331.1 deoxyguanosinetriphosphate triphosphohydrolase -
LP122_RS01620 (LP122_01595) 357707..358000 + 294 WP_264677330.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP122_RS01625 (LP122_01600) 357993..358265 + 273 WP_228157760.1 type II toxin-antitoxin system YafQ family toxin Toxin
LP122_RS01630 (LP122_01605) 358330..358785 - 456 WP_264677329.1 type IV secretion protein Rhs -
LP122_RS01635 (LP122_01610) 358845..359114 + 270 WP_264677328.1 hypothetical protein -
LP122_RS01640 (LP122_01615) 359111..359491 + 381 WP_264677327.1 type II toxin-antitoxin system VapC family toxin -
LP122_RS01645 (LP122_01620) 359488..360747 + 1260 WP_264677326.1 replication-associated recombination protein A -
LP122_RS01650 (LP122_01625) 360827..361090 + 264 WP_264675982.1 type II toxin-antitoxin system VapB family antitoxin -
LP122_RS01655 (LP122_01630) 361087..361479 + 393 WP_264677325.1 type II toxin-antitoxin system VapC family toxin -
LP122_RS01660 (LP122_01635) 361602..362132 + 531 WP_264678418.1 glucose-6-phosphate 1-dehydrogenase family protein -
LP122_RS01665 (LP122_01640) 362129..362695 - 567 WP_078275186.1 hypothetical protein -
LP122_RS01670 (LP122_01645) 362698..362934 - 237 WP_078275185.1 sulfurtransferase TusA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-52)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10415.99 Da        Isoelectric Point: 6.9668

>T226426 WP_228157760.1 NZ_CP087865:357993-358265 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG

Download         Length: 273 bp

>T226426 NZ_CP122469:c4749291-4749007 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGGCCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11096.37 Da        Isoelectric Point: 4.7769

>AT226426 WP_264677330.1 NZ_CP087865:357707-358000 [Moraxella bovis]
MSHTNFNMRLDNDLRQKVYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG

Download         Length: 294 bp

>AT226426 NZ_CP122469:c4749523-4749281 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCGGGGGTTAAGGTGAGTCTGGATGACCTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References