Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 639484..640133 Replicon chromosome
Accession NZ_CP087862
Organism Moraxella bovis strain SAM57979

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LP105_RS03400 Protein ID WP_264677937.1
Coordinates 639732..640133 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LP105_RS03395 Protein ID WP_112741908.1
Coordinates 639484..639717 (+) Length 78 a.a.

Genomic Context


LP105_RS03390LP105_RS03395LP105_RS03400LP105_RS03405LP105_RS03410LP105_RS03375LP105_RS03380LP105_RS03385LP105_RS03415LP105_RS03425LP105_RS03430
Location: 637337..639436 (2100 bp)
Type: Others
Protein ID: WP_264683682.1
Location: 639484..639717 (234 bp)
Type: Antitoxin
Protein ID: WP_112741908.1
Location: 639732..640133 (402 bp)
Type: Toxin
Protein ID: WP_264677937.1
Location: 640657..641157 (501 bp)
Type: Others
Protein ID: WP_112741909.1
Location: 641279..642109 (831 bp)
Type: Others
Protein ID: WP_264677938.1
Location: 634880..635329 (450 bp)
Type: Others
Protein ID: WP_264683685.1
Location: 635511..636503 (993 bp)
Type: Others
Protein ID: WP_264683684.1
Location: 636523..637116 (594 bp)
Type: Others
Protein ID: WP_208624078.1
Location: 642209..642898 (690 bp)
Type: Others
Protein ID: WP_264677939.1
Location: 643636..644055 (420 bp)
Type: Others
Protein ID: WP_264677940.1
Location: 644307..644480 (174 bp)
Type: Others
Protein ID: WP_264677941.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP105_RS03375 (LP105_03355)634880..635329-450WP_264683685.1cytochrome c-
LP105_RS03380 (LP105_03360)635511..636503-993WP_264683684.1oxygen-dependent coproporphyrinogen oxidase-
LP105_RS03385 (LP105_03365)636523..637116-594WP_208624078.1GTP cyclohydrolase II-
LP105_RS03390 (LP105_03370)637337..639436+2100WP_264683682.11-deoxy-D-xylulose-5-phosphate synthase-
LP105_RS03395 (LP105_03375)639484..639717+234WP_112741908.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
LP105_RS03400 (LP105_03380)639732..640133+402WP_264677937.1type II toxin-antitoxin system VapC family toxinToxin
LP105_RS03405 (LP105_03385)640657..641157+501WP_112741909.1WG repeat-containing protein-
LP105_RS03410 (LP105_03390)641279..642109+831WP_264677938.1inositol monophosphatase family protein-
LP105_RS03415 (LP105_03395)642209..642898-690WP_264677939.1SIMPL domain-containing protein-
LP105_RS03425 (LP105_03405)643636..644055-420WP_264677940.1S4 domain-containing protein-
LP105_RS03430 (LP105_03410)644307..644480-174WP_264677941.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-125)

Antitoxin

(8-54)


Sequences


Toxin        


Download         Length: 134 a.a.        Molecular weight: 15071.29 Da        Isoelectric Point: 6.8426

>T226411 WP_264677937.1 NZ_CP087862:639732-640133 [Moraxella bovis]
MFSFMLDTNICIYVIKERPIKALNKFNQYAGRICVSSIVASELYFGAYNSQFMDKNLHQVEDFLSRLTVLDYTAECSPHY
GEICADLTKQGKLISENDIHIASHARALGLTLITNNTDEFKRVSGLRIGNWAI

Download         Length: 402 bp

>T226411 NZ_CP122461:c2572384-2571062 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGAGGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGCGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8990.22 Da        Isoelectric Point: 6.2884

>AT226411 WP_112741908.1 NZ_CP087862:639484-639717 [Moraxella bovis]
MQTSVFFNNRTQAVRIPAKFRFDDDVKAVMIRKVGNERILTPIDGVWDSFFLSDERASDDFMANRPTMPKSERLTFD

Download         Length: 234 bp

>AT226411 NZ_CP122461:c2572650-2572384 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References