Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1571415..1571904 Replicon chromosome
Accession NZ_CP087859
Organism Moraxella bovis strain SAM57983

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP093_RS07710 Protein ID WP_112742208.1
Coordinates 1571415..1571672 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP093_RS07715 Protein ID WP_228157840.1
Coordinates 1571662..1571904 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP093_RS07695 (LP093_07620) 1567360..1569882 + 2523 WP_112742210.1 alpha/beta hydrolase -
LP093_RS07700 (LP093_07625) 1569978..1570781 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP093_RS07705 (LP093_07630) 1570847..1571356 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP093_RS07710 (LP093_07635) 1571415..1571672 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP093_RS07715 (LP093_07640) 1571662..1571904 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP093_RS07720 (LP093_07645) 1571949..1572113 + 165 WP_162860378.1 hypothetical protein -
LP093_RS07725 (LP093_07650) 1572195..1572482 - 288 WP_078273310.1 DUF1315 family protein -
LP093_RS07730 (LP093_07655) 1572726..1573959 - 1234 Protein_1504 DUF853 family protein -
LP093_RS07735 (LP093_07660) 1574122..1574640 - 519 WP_264676264.1 bestrophin family protein -
LP093_RS07740 (LP093_07665) 1574630..1574842 - 213 WP_264676263.1 bestrophin family protein -
LP093_RS07745 (LP093_07670) 1574839..1575636 - 798 WP_264676262.1 polyphenol oxidase family protein -
LP093_RS07750 (LP093_07675) 1575755..1576804 - 1050 WP_264676261.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1564392..1614021 49629


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226403 WP_112742208.1 NZ_CP087859:c1571672-1571415 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226403 NZ_CP122457:c4581241-4580867 [Salmonella enterica subsp. enterica]
ATGGTCAAAGGGTCTGCGCTTTTTGATACCAATATCCTCATCGATCTGTTTAGCGGTCGAATTGAAGCGAAACATGCGCT
GGAAGCGTATCCGCCACAGAATGCGATTAGCCTTATCACATGGATGGAAGTGATGGTGGGTGCTAAGAAATATCATCAGG
AAAACCGCACGCGCATTGCATTAAGTGCGTTCAATATTATTGGCGTAACACAGGAAATCGCGGAGCGAAGCGTCATTGTC
AGGCAGGAATATGGCATGAAACTCCCGGATGCGATCATTCTGGCCACTGCACAAGTCCATCGTTGTGAGCTTGTGACGCG
TAATACAAAAGACTTTGCCGATATTCCGGGAGTGATCACACCGTATCACTTGTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226403 WP_228157840.1 NZ_CP087859:c1571904-1571662 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226403 NZ_CP122457:c4581483-4581241 [Salmonella enterica subsp. enterica]
ATGATGGCTGGGATGGATATGGGCAGAATTTTACTCGATTTATCAGACGACGTGATTAAACGGCTTGACGATCTCAAGGT
GCAACGCAACCTGCCTCGTGCAGAACTCTTGCGGGAGGCCGTTGAGCAGTATCTGGAAAGACAGGATCGGGCTGAGACCA
CAATTTCGAAAGCATTGGGGCTCTGGCAAGGCTGTGAGGAAGATGGCGTTGAATACCAACGTAAACTTCGTGAGGAATGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References