Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 2295251..2295809 Replicon chromosome
Accession NZ_CP087856
Organism Moraxella bovis strain SAM57987

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP115_RS11760 Protein ID WP_228157760.1
Coordinates 2295251..2295523 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1S9ZVK6
Locus tag LP115_RS11765 Protein ID WP_029103533.1
Coordinates 2295516..2295809 (-) Length 98 a.a.

Genomic Context


LP115_RS11720LP115_RS11725LP115_RS11755LP115_RS11785LP115_RS11730LP115_RS11735LP115_RS11740LP115_RS11745LP115_RS11750LP115_RS11760LP115_RS11765LP115_RS11770LP115_RS11775LP115_RS11780
Location: 2290465..2290701 (237 bp)
Type: Others
Protein ID: WP_078275185.1
Location: 2290704..2291270 (567 bp)
Type: Others
Protein ID: WP_078275186.1
Location: 2294731..2295186 (456 bp)
Type: Others
Protein ID: WP_264675985.1
Location: 2298964..2300298 (1335 bp)
Type: Others
Protein ID: WP_078275195.1
Location: 2291267..2291797 (531 bp)
Type: Others
Protein ID: WP_078275187.1
Location: 2291920..2292312 (393 bp)
Type: Others
Protein ID: WP_078275188.1
Location: 2292309..2292572 (264 bp)
Type: Others
Protein ID: WP_264675982.1
Location: 2292652..2293911 (1260 bp)
Type: Others
Protein ID: WP_264675983.1
Location: 2294269..2294646 (378 bp)
Type: Others
Protein ID: WP_264675984.1
Location: 2295251..2295523 (273 bp)
Type: Toxin
Protein ID: WP_228157760.1
Location: 2295516..2295809 (294 bp)
Type: Antitoxin
Protein ID: WP_029103533.1
Location: 2295953..2297287 (1335 bp)
Type: Others
Protein ID: WP_112741795.1
Location: 2297496..2298212 (717 bp)
Type: Others
Protein ID: WP_078275193.1
Location: 2298233..2298844 (612 bp)
Type: Others
Protein ID: WP_112741794.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP115_RS11720 (LP115_11615)2290465..2290701+237WP_078275185.1sulfurtransferase TusA-
LP115_RS11725 (LP115_11620)2290704..2291270+567WP_078275186.1hypothetical protein-
LP115_RS11730 (LP115_11625)2291267..2291797-531WP_078275187.1HI_0552 family protein-
LP115_RS11735 (LP115_11630)2291920..2292312-393WP_078275188.1type II toxin-antitoxin system VapC family toxin-
LP115_RS11740 (LP115_11635)2292309..2292572-264WP_264675982.1type II toxin-antitoxin system VapB family antitoxin-
LP115_RS11745 (LP115_11640)2292652..2293911-1260WP_264675983.1replication-associated recombination protein A-
LP115_RS11750 (LP115_11645)2294269..2294646-378WP_264675984.1hypothetical protein-
LP115_RS11755 (LP115_11650)2294731..2295186+456WP_264675985.1type IV secretion protein Rhs-
LP115_RS11760 (LP115_11655)2295251..2295523-273WP_228157760.1type II toxin-antitoxin system YafQ family toxinToxin
LP115_RS11765 (LP115_11660)2295516..2295809-294WP_029103533.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
LP115_RS11770 (LP115_11665)2295953..2297287-1335WP_112741795.1deoxyguanosinetriphosphate triphosphohydrolase-
LP115_RS11775 (LP115_11670)2297496..2298212-717WP_078275193.1hypothetical protein-
LP115_RS11780 (LP115_11675)2298233..2298844-612WP_112741794.1methyltransferase-
LP115_RS11785 (LP115_11680)2298964..2300298+1335WP_078275195.1valine--pyruvate transaminase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-90)

Antitoxin

(1-67)


Sequences


Toxin        


Download         Length: 91 a.a.        Molecular weight: 10415.99 Da        Isoelectric Point: 6.9668

>T226396 WP_228157760.1 NZ_CP087856:c2295523-2295251 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG

Download         Length: 273 bp

>T226396 NZ_CP122457:c1004323-1003796 [Salmonella enterica subsp. enterica]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATACGATGTGCCAGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTGGCGTAGCCCTGCTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11068.31 Da        Isoelectric Point: 4.7769

>AT226396 WP_029103533.1 NZ_CP087856:c2295809-2295516 [Moraxella bovis]
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG

Download         Length: 294 bp

>AT226396 NZ_CP122457:c1004610-1004320 [Salmonella enterica subsp. enterica]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTACGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACGTACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGCGATACTCAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCTGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1S9ZVK6

References