Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YafQ-RelB |
Location | 2295251..2295809 | Replicon | chromosome |
Accession | NZ_CP087856 | ||
Organism | Moraxella bovis strain SAM57987 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | LP115_RS11760 | Protein ID | WP_228157760.1 |
Coordinates | 2295251..2295523 (-) | Length | 91 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A1S9ZVK6 |
Locus tag | LP115_RS11765 | Protein ID | WP_029103533.1 |
Coordinates | 2295516..2295809 (-) | Length | 98 a.a. |
Genomic Context
Location: 2290465..2290701 (237 bp)
Type: Others
Protein ID: WP_078275185.1
Type: Others
Protein ID: WP_078275185.1
Location: 2290704..2291270 (567 bp)
Type: Others
Protein ID: WP_078275186.1
Type: Others
Protein ID: WP_078275186.1
Location: 2294731..2295186 (456 bp)
Type: Others
Protein ID: WP_264675985.1
Type: Others
Protein ID: WP_264675985.1
Location: 2298964..2300298 (1335 bp)
Type: Others
Protein ID: WP_078275195.1
Type: Others
Protein ID: WP_078275195.1
Location: 2291267..2291797 (531 bp)
Type: Others
Protein ID: WP_078275187.1
Type: Others
Protein ID: WP_078275187.1
Location: 2291920..2292312 (393 bp)
Type: Others
Protein ID: WP_078275188.1
Type: Others
Protein ID: WP_078275188.1
Location: 2292309..2292572 (264 bp)
Type: Others
Protein ID: WP_264675982.1
Type: Others
Protein ID: WP_264675982.1
Location: 2292652..2293911 (1260 bp)
Type: Others
Protein ID: WP_264675983.1
Type: Others
Protein ID: WP_264675983.1
Location: 2294269..2294646 (378 bp)
Type: Others
Protein ID: WP_264675984.1
Type: Others
Protein ID: WP_264675984.1
Location: 2295251..2295523 (273 bp)
Type: Toxin
Protein ID: WP_228157760.1
Type: Toxin
Protein ID: WP_228157760.1
Location: 2295516..2295809 (294 bp)
Type: Antitoxin
Protein ID: WP_029103533.1
Type: Antitoxin
Protein ID: WP_029103533.1
Location: 2295953..2297287 (1335 bp)
Type: Others
Protein ID: WP_112741795.1
Type: Others
Protein ID: WP_112741795.1
Location: 2297496..2298212 (717 bp)
Type: Others
Protein ID: WP_078275193.1
Type: Others
Protein ID: WP_078275193.1
Location: 2298233..2298844 (612 bp)
Type: Others
Protein ID: WP_112741794.1
Type: Others
Protein ID: WP_112741794.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LP115_RS11720 (LP115_11615) | 2290465..2290701 | + | 237 | WP_078275185.1 | sulfurtransferase TusA | - |
LP115_RS11725 (LP115_11620) | 2290704..2291270 | + | 567 | WP_078275186.1 | hypothetical protein | - |
LP115_RS11730 (LP115_11625) | 2291267..2291797 | - | 531 | WP_078275187.1 | HI_0552 family protein | - |
LP115_RS11735 (LP115_11630) | 2291920..2292312 | - | 393 | WP_078275188.1 | type II toxin-antitoxin system VapC family toxin | - |
LP115_RS11740 (LP115_11635) | 2292309..2292572 | - | 264 | WP_264675982.1 | type II toxin-antitoxin system VapB family antitoxin | - |
LP115_RS11745 (LP115_11640) | 2292652..2293911 | - | 1260 | WP_264675983.1 | replication-associated recombination protein A | - |
LP115_RS11750 (LP115_11645) | 2294269..2294646 | - | 378 | WP_264675984.1 | hypothetical protein | - |
LP115_RS11755 (LP115_11650) | 2294731..2295186 | + | 456 | WP_264675985.1 | type IV secretion protein Rhs | - |
LP115_RS11760 (LP115_11655) | 2295251..2295523 | - | 273 | WP_228157760.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
LP115_RS11765 (LP115_11660) | 2295516..2295809 | - | 294 | WP_029103533.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
LP115_RS11770 (LP115_11665) | 2295953..2297287 | - | 1335 | WP_112741795.1 | deoxyguanosinetriphosphate triphosphohydrolase | - |
LP115_RS11775 (LP115_11670) | 2297496..2298212 | - | 717 | WP_078275193.1 | hypothetical protein | - |
LP115_RS11780 (LP115_11675) | 2298233..2298844 | - | 612 | WP_112741794.1 | methyltransferase | - |
LP115_RS11785 (LP115_11680) | 2298964..2300298 | + | 1335 | WP_078275195.1 | valine--pyruvate transaminase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10415.99 Da Isoelectric Point: 6.9668
>T226396 WP_228157760.1 NZ_CP087856:c2295523-2295251 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
Download Length: 273 bp
>T226396 NZ_CP122457:c1004323-1003796 [Salmonella enterica subsp. enterica]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATACGATGTGCCAGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTGGCGTAGCCCTGCTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATACGATGTGCCAGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTGGCGTAGCCCTGCTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 11068.31 Da Isoelectric Point: 4.7769
>AT226396 WP_029103533.1 NZ_CP087856:c2295809-2295516 [Moraxella bovis]
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
Download Length: 294 bp
>AT226396 NZ_CP122457:c1004610-1004320 [Salmonella enterica subsp. enterica]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTACGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACGTACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGCGATACTCAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCTGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTACGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACGTACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGCGATACTCAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCTGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1S9ZVK6 |