Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1169916..1170405 Replicon chromosome
Accession NZ_CP087856
Organism Moraxella bovis strain SAM57987

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP115_RS06320 Protein ID WP_112742208.1
Coordinates 1170148..1170405 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP115_RS06315 Protein ID WP_228157840.1
Coordinates 1169916..1170158 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP115_RS06280 (LP115_06235) 1165016..1166065 + 1050 WP_264676261.1 RluA family pseudouridine synthase -
LP115_RS06285 (LP115_06240) 1166184..1166981 + 798 WP_264676262.1 polyphenol oxidase family protein -
LP115_RS06290 1166978..1167190 + 213 WP_264676263.1 bestrophin family protein -
LP115_RS06295 (LP115_06245) 1167180..1167698 + 519 WP_264676264.1 bestrophin family protein -
LP115_RS06300 (LP115_06250) 1167861..1169094 + 1234 Protein_1231 DUF853 family protein -
LP115_RS06305 (LP115_06255) 1169338..1169625 + 288 WP_078273310.1 DUF1315 family protein -
LP115_RS06310 (LP115_06260) 1169707..1169871 - 165 WP_162860378.1 hypothetical protein -
LP115_RS06315 (LP115_06265) 1169916..1170158 + 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP115_RS06320 (LP115_06270) 1170148..1170405 + 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP115_RS06325 (LP115_06275) 1170464..1170973 + 510 WP_112742209.1 peptidylprolyl isomerase -
LP115_RS06330 (LP115_06280) 1171039..1171842 + 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP115_RS06335 (LP115_06285) 1171938..1174460 - 2523 WP_112742210.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226392 WP_112742208.1 NZ_CP087856:1170148-1170405 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226392 NZ_CP122456:4190-4465 [Escherichia coli]
ATGGAACTGAAGTGGACCAGTAAGGCACTTTCTGATTTGGCGCGGTTATATGATTTTCTGGTACTGGCCAGTAAACCTGC
TGCCGCCAGAACGGTGCAGTCCCTGACACAGGCGCCGGTCATTCTGTTAACTCATCCACGTATGGGAGAACAGTTGTTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTTTGCTGGCGAGTACGAAATCCGTTATGAACTTACTGGCCAGACTATTTAT
GTATTGCGCCTGTGGCACACACGAGAAAACAGGTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226392 WP_228157840.1 NZ_CP087856:1169916-1170158 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226392 NZ_CP122456:3906-4190 [Escherichia coli]
ATGCAAATGAAAAACAATACCGCACAAACAACAAAAGTCATTACCGCGCATGTGCCATTACCTATGGCTGATAAAATCGA
CCAGATGGCCGCCAGACTGGAACGCTCCCGGGGCTGGATTATCAAACAGGCGCTTTCTGCATGGCTTGCCCAGGAGGAGG
AGCGTAATCGCCTGACGCTGGAAGCCCTGGACGATGTGACATCCGGACAGGTTATCGACCATCAGGCTGTACAGGCCTGG
GCAGACAGCCTCAATACTGACAATCCGTTACCGGTGCCTCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References