Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafQ-RelB |
| Location | 2425429..2425987 | Replicon | chromosome |
| Accession | NZ_CP087854 | ||
| Organism | Moraxella bovis strain SAM57990 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LP113_RS12395 | Protein ID | WP_228157760.1 |
| Coordinates | 2425429..2425701 (-) | Length | 91 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A1S9ZVK6 |
| Locus tag | LP113_RS12400 | Protein ID | WP_029103533.1 |
| Coordinates | 2425694..2425987 (-) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LP113_RS12355 (LP113_12265) | 2420675..2420911 | + | 237 | WP_078275185.1 | sulfurtransferase TusA | - |
| LP113_RS12360 (LP113_12270) | 2420914..2421480 | + | 567 | WP_078275186.1 | hypothetical protein | - |
| LP113_RS12365 (LP113_12275) | 2421477..2422007 | - | 531 | WP_078275187.1 | HI_0552 family protein | - |
| LP113_RS12370 (LP113_12280) | 2422130..2422522 | - | 393 | WP_078275188.1 | type II toxin-antitoxin system VapC family toxin | - |
| LP113_RS12375 (LP113_12285) | 2422519..2422782 | - | 264 | WP_078275189.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| LP113_RS12380 (LP113_12290) | 2422862..2424121 | - | 1260 | WP_078275190.1 | replication-associated recombination protein A | - |
| LP113_RS12385 (LP113_12295) | 2424100..2424873 | - | 774 | WP_078275191.1 | hypothetical protein | - |
| LP113_RS12390 (LP113_12300) | 2424924..2425364 | + | 441 | WP_208624064.1 | type IV secretion protein Rhs | - |
| LP113_RS12395 (LP113_12305) | 2425429..2425701 | - | 273 | WP_228157760.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| LP113_RS12400 (LP113_12310) | 2425694..2425987 | - | 294 | WP_029103533.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LP113_RS12405 (LP113_12315) | 2426131..2427465 | - | 1335 | WP_112741795.1 | deoxyguanosinetriphosphate triphosphohydrolase | - |
| LP113_RS12410 (LP113_12320) | 2427674..2428390 | - | 717 | WP_078275193.1 | hypothetical protein | - |
| LP113_RS12415 (LP113_12325) | 2428411..2429022 | - | 612 | WP_112741794.1 | methyltransferase | - |
| LP113_RS12420 (LP113_12330) | 2429142..2430476 | + | 1335 | WP_078275195.1 | valine--pyruvate transaminase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10415.99 Da Isoelectric Point: 6.9668
>T226385 WP_228157760.1 NZ_CP087854:c2425701-2425429 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
Download Length: 273 bp
>T226385 NZ_CP122454:c4112246-4111935 [Escherichia coli]
ATGCACATCATTTCTAAAGCGCCATTTGAAGAGTCTGCGCGTAAATATCCTAACGACGCTCTGGCTCTTCAGGCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACGCCAGAAGAAATGCGAACGGCGTTTCCCAACCTCGACAATTTTAAATATC
GCAACAAATGGTACGTTCTGGATGTAGGTGGGAACAACCTAAGGGTGATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACTAATCACGCCGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA
ATGCACATCATTTCTAAAGCGCCATTTGAAGAGTCTGCGCGTAAATATCCTAACGACGCTCTGGCTCTTCAGGCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACGCCAGAAGAAATGCGAACGGCGTTTCCCAACCTCGACAATTTTAAATATC
GCAACAAATGGTACGTTCTGGATGTAGGTGGGAACAACCTAAGGGTGATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACTAATCACGCCGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 11068.31 Da Isoelectric Point: 4.7769
>AT226385 WP_029103533.1 NZ_CP087854:c2425987-2425694 [Moraxella bovis]
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
Download Length: 294 bp
>AT226385 NZ_CP122454:c4111938-4111519 [Escherichia coli]
ATGACTGCTAATGCTGTACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGCAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGACGAGCCGCATTGCAGAATATGAAAACAACAACGAAAAGTTTGCAGAGTTCGACAAAGCCGTTGCGGCAATGCCTGTT
GGTGTGGCGTTACTTCGCACGCTGATTGATCAACATAATCTGACCTATGCGGATTTGAAGAACGAAATCGGCTCTAAATC
CCTGGTCAGCCAGATCTTGTCTGGACAACGATCCTTGACGATATCCCACATTAAGGCACTTTCAGCCCGATTTGGCGTTA
AGCCGGAATGGTTTCTTTGA
ATGACTGCTAATGCTGTACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGCAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGACGAGCCGCATTGCAGAATATGAAAACAACAACGAAAAGTTTGCAGAGTTCGACAAAGCCGTTGCGGCAATGCCTGTT
GGTGTGGCGTTACTTCGCACGCTGATTGATCAACATAATCTGACCTATGCGGATTTGAAGAACGAAATCGGCTCTAAATC
CCTGGTCAGCCAGATCTTGTCTGGACAACGATCCTTGACGATATCCCACATTAAGGCACTTTCAGCCCGATTTGGCGTTA
AGCCGGAATGGTTTCTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|