Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1169394..1169883 Replicon chromosome
Accession NZ_CP087851
Organism Moraxella bovis strain SAM57991

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP094_RS06310 Protein ID WP_112742208.1
Coordinates 1169626..1169883 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP094_RS06305 Protein ID WP_228157840.1
Coordinates 1169394..1169636 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP094_RS06270 (LP094_06240) 1164494..1165543 + 1050 WP_264676261.1 RluA family pseudouridine synthase -
LP094_RS06275 (LP094_06245) 1165662..1166459 + 798 WP_264676262.1 polyphenol oxidase family protein -
LP094_RS06280 1166456..1166668 + 213 WP_264676263.1 bestrophin family protein -
LP094_RS06285 (LP094_06250) 1166658..1167176 + 519 WP_264676264.1 bestrophin family protein -
LP094_RS06290 (LP094_06255) 1167339..1168572 + 1234 Protein_1228 DUF853 family protein -
LP094_RS06295 (LP094_06260) 1168816..1169103 + 288 WP_078273310.1 DUF1315 family protein -
LP094_RS06300 (LP094_06265) 1169185..1169349 - 165 WP_162860378.1 hypothetical protein -
LP094_RS06305 (LP094_06270) 1169394..1169636 + 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP094_RS06310 (LP094_06275) 1169626..1169883 + 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP094_RS06315 (LP094_06280) 1169942..1170451 + 510 WP_112742209.1 peptidylprolyl isomerase -
LP094_RS06320 (LP094_06285) 1170517..1171320 + 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP094_RS06325 (LP094_06290) 1171416..1173938 - 2523 WP_112742210.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226371 WP_112742208.1 NZ_CP087851:1169626-1169883 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226371 NZ_CP122454:178342-178449 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226371 WP_228157840.1 NZ_CP087851:1169394-1169636 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226371 NZ_CP122454:c178294-178228 [Escherichia coli]
GGTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References