Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) AbkB-shpB/BrnT-BrnA
Location 965240..965792 Replicon chromosome
Accession NZ_CP087851
Organism Moraxella bovis strain SAM57991

Toxin (Protein)


Gene name AbkB Uniprot ID A0A1T0A7D3
Locus tag LP094_RS05140 Protein ID WP_029102268.1
Coordinates 965514..965792 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LP094_RS05135 Protein ID WP_078273473.1
Coordinates 965240..965527 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP094_RS05120 (LP094_05105) 960675..961724 + 1050 WP_264676228.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
LP094_RS05125 (LP094_05110) 961803..963302 + 1500 WP_112742120.1 DUF389 domain-containing protein -
LP094_RS05130 (LP094_05115) 963500..965230 - 1731 WP_078273474.1 flotillin domain-containing protein -
LP094_RS05135 (LP094_05120) 965240..965527 - 288 WP_078273473.1 BrnA antitoxin family protein Antitoxin
LP094_RS05140 (LP094_05125) 965514..965792 - 279 WP_029102268.1 BrnT family toxin Toxin
LP094_RS05145 (LP094_05130) 965887..966543 - 657 WP_078273472.1 YqiJ family protein -
LP094_RS05150 (LP094_05135) 966743..967408 - 666 WP_078273471.1 PspA/IM30 family protein -
LP094_RS05155 (LP094_05140) 967621..967911 - 291 WP_264676229.1 hypothetical protein -
LP094_RS05160 (LP094_05145) 967904..968419 - 516 WP_115369660.1 hypothetical protein -
LP094_RS05165 (LP094_05150) 968567..968917 - 351 WP_078273468.1 TIGR01244 family sulfur transferase -
LP094_RS05170 (LP094_05155) 969029..969805 + 777 WP_264676230.1 nucleotidyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-85)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(36-89)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10484.81 Da        Isoelectric Point: 5.1084

>T226370 WP_029102268.1 NZ_CP087851:c965792-965514 [Moraxella bovis]
MIFEWDDNKNRTNKQKHGVSFESASRIFLDPFLIVTEDTSSDEVRWLGVGSVDGVVILLVVHTHTDTDGTEIIRIISARK
LSRGEIERYGYC

Download         Length: 279 bp

>T226370 NZ_CP122454:177859-177966 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGTTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10979.71 Da        Isoelectric Point: 7.0097

>AT226370 WP_078273473.1 NZ_CP087851:c965527-965240 [Moraxella bovis]
MAIVRKTLDDIKHTPIDKDELAQLQSMSDDSINYDDIPPLTDVQIANLRLYKPIKQQITLRLDSDIVAWLKKDGKGYQTR
ANQLLRQLMLKELTT

Download         Length: 288 bp

>AT226370 NZ_CP122454:c177811-177745 [Escherichia coli]
GGTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1T0A7D3

Antitoxin

Source ID Structure

References