Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 743135..743712 Replicon chromosome
Accession NZ_CP087851
Organism Moraxella bovis strain SAM57991

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP094_RS03940 Protein ID WP_078275234.1
Coordinates 743377..743712 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP094_RS03935 Protein ID WP_078275235.1
Coordinates 743135..743377 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP094_RS03910 (LP094_03895) 739034..739456 - 423 WP_078275239.1 hypothetical protein -
LP094_RS03915 (LP094_03900) 739465..739770 - 306 WP_078275238.1 YciI family protein -
LP094_RS03920 (LP094_03905) 739930..740556 - 627 WP_078275237.1 septation protein IspZ -
LP094_RS03925 (LP094_03910) 740745..741467 + 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP094_RS03930 (LP094_03915) 741849..742928 - 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP094_RS03935 (LP094_03920) 743135..743377 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP094_RS03940 (LP094_03925) 743377..743712 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP094_RS03945 (LP094_03930) 743774..744769 + 996 WP_208624081.1 polyprenyl synthetase family protein -
LP094_RS03950 (LP094_03935) 744841..745029 + 189 WP_143821748.1 hypothetical protein -
LP094_RS03955 (LP094_03940) 745119..747263 - 2145 WP_264676147.1 cation-translocating P-type ATPase -
LP094_RS03960 (LP094_03945) 747428..748012 - 585 WP_112741954.1 hypothetical protein -
LP094_RS03965 (LP094_03950) 748172..748372 - 201 WP_112741955.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226368 WP_078275234.1 NZ_CP087851:743377-743712 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226368 NZ_CP122452:49401-49706 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTTCAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCCCGCCTGCTGTCAGACAAAGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGTCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226368 WP_078275235.1 NZ_CP087851:743135-743377 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226368 NZ_CP122452:49181-49399 [Escherichia coli]
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAATTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACAACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCCGATGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References