Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1154870..1155359 Replicon chromosome
Accession NZ_CP087844
Organism Moraxella bovis strain SAM58105

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP103_RS06175 Protein ID WP_112742208.1
Coordinates 1155102..1155359 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP103_RS06170 Protein ID WP_228157840.1
Coordinates 1154870..1155112 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP103_RS06135 (LP103_06090) 1149970..1151019 + 1050 WP_264676261.1 RluA family pseudouridine synthase -
LP103_RS06140 (LP103_06095) 1151138..1151935 + 798 WP_264676262.1 polyphenol oxidase family protein -
LP103_RS06145 1151932..1152144 + 213 WP_264676263.1 bestrophin family protein -
LP103_RS06150 (LP103_06100) 1152134..1152652 + 519 WP_264676264.1 bestrophin family protein -
LP103_RS06155 (LP103_06105) 1152815..1154048 + 1234 Protein_1202 DUF853 family protein -
LP103_RS06160 (LP103_06110) 1154292..1154579 + 288 WP_078273310.1 DUF1315 family protein -
LP103_RS06165 (LP103_06115) 1154661..1154825 - 165 WP_162860378.1 hypothetical protein -
LP103_RS06170 (LP103_06120) 1154870..1155112 + 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP103_RS06175 (LP103_06125) 1155102..1155359 + 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP103_RS06180 (LP103_06130) 1155418..1155927 + 510 WP_112742209.1 peptidylprolyl isomerase -
LP103_RS06185 (LP103_06135) 1155993..1156796 + 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP103_RS06190 (LP103_06140) 1156892..1159414 - 2523 WP_112742210.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226350 WP_112742208.1 NZ_CP087844:1155102-1155359 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226350 NZ_CP122451:c815356-814979 [Escherichia coli]
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGTGCTGCCCGTCTCCCGTCACCATCTGGCATACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACCGAACAGTAAATAACATTACTCTGGGTAAGCATCCGGAGGCGAAACAATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226350 WP_228157840.1 NZ_CP087844:1154870-1155112 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226350 NZ_CP122451:c815777-815403 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAGCTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGGCCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References