Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 742360..742937 Replicon chromosome
Accession NZ_CP087844
Organism Moraxella bovis strain SAM58105

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP103_RS03920 Protein ID WP_078275234.1
Coordinates 742602..742937 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP103_RS03915 Protein ID WP_078275235.1
Coordinates 742360..742602 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP103_RS03890 (LP103_03870) 738259..738681 - 423 WP_078275239.1 hypothetical protein -
LP103_RS03895 (LP103_03875) 738690..738995 - 306 WP_078275238.1 YciI family protein -
LP103_RS03900 (LP103_03880) 739155..739781 - 627 WP_078275237.1 septation protein IspZ -
LP103_RS03905 (LP103_03885) 739970..740692 + 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP103_RS03910 (LP103_03890) 741074..742153 - 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP103_RS03915 (LP103_03895) 742360..742602 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP103_RS03920 (LP103_03900) 742602..742937 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP103_RS03925 (LP103_03905) 742999..743994 + 996 WP_208624081.1 polyprenyl synthetase family protein -
LP103_RS03930 (LP103_03910) 744066..744254 + 189 WP_143821748.1 hypothetical protein -
LP103_RS03935 (LP103_03915) 744344..746488 - 2145 WP_264676147.1 cation-translocating P-type ATPase -
LP103_RS03940 (LP103_03920) 746653..747237 - 585 WP_112741954.1 hypothetical protein -
LP103_RS03945 (LP103_03925) 747397..747597 - 201 WP_112741955.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226347 WP_078275234.1 NZ_CP087844:742602-742937 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226347 NZ_CP122451:177859-177966 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGTTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226347 WP_078275235.1 NZ_CP087844:742360-742602 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226347 NZ_CP122451:c177811-177745 [Escherichia coli]
GGTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References