Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2445388..2445965 Replicon chromosome
Accession NZ_CP087843
Organism Moraxella bovis strain SAM58106

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP121_RS12325 Protein ID WP_078275234.1
Coordinates 2445388..2445723 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP121_RS12330 Protein ID WP_078275235.1
Coordinates 2445723..2445965 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP121_RS12300 (LP121_12195) 2440729..2440929 + 201 WP_112741955.1 hypothetical protein -
LP121_RS12305 (LP121_12200) 2441142..2441672 + 531 WP_264684205.1 hypothetical protein -
LP121_RS12310 (LP121_12205) 2441837..2443981 + 2145 WP_264684206.1 cation-translocating P-type ATPase -
LP121_RS12315 (LP121_12210) 2444071..2444307 - 237 WP_264684207.1 hypothetical protein -
LP121_RS12320 (LP121_12215) 2444331..2445326 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP121_RS12325 (LP121_12220) 2445388..2445723 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP121_RS12330 (LP121_12225) 2445723..2445965 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP121_RS12335 (LP121_12230) 2446172..2447251 + 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP121_RS12340 (LP121_12235) 2447633..2448355 - 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP121_RS12345 (LP121_12240) 2448544..2449170 + 627 WP_078275237.1 septation protein IspZ -
LP121_RS12350 (LP121_12245) 2449330..2449635 + 306 WP_078275238.1 YciI family protein -
LP121_RS12355 (LP121_12250) 2449644..2450066 + 423 WP_078275239.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226341 WP_078275234.1 NZ_CP087843:c2445723-2445388 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226341 NZ_CP122448:4294491-4294832 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACTGCGGTAGATGTCAAAGTAATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTCGCCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226341 WP_078275235.1 NZ_CP087843:c2445965-2445723 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226341 NZ_CP122448:c4294496-4294420 [Escherichia coli]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References