Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 2011450..2011939 Replicon chromosome
Accession NZ_CP087843
Organism Moraxella bovis strain SAM58106

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP121_RS09915 Protein ID WP_112742208.1
Coordinates 2011450..2011707 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP121_RS09920 Protein ID WP_228157840.1
Coordinates 2011697..2011939 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP121_RS09900 (LP121_09815) 2007395..2009917 + 2523 WP_264684167.1 alpha/beta hydrolase -
LP121_RS09905 (LP121_09820) 2010013..2010816 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP121_RS09910 (LP121_09825) 2010882..2011391 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP121_RS09915 (LP121_09830) 2011450..2011707 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP121_RS09920 (LP121_09835) 2011697..2011939 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP121_RS09925 (LP121_09840) 2011984..2012148 + 165 WP_162860378.1 hypothetical protein -
LP121_RS09930 (LP121_09845) 2012230..2012517 - 288 WP_078273310.1 DUF1315 family protein -
LP121_RS09935 (LP121_09850) 2012761..2013994 - 1234 Protein_1941 DUF853 family protein -
LP121_RS09940 (LP121_09855) 2014157..2014675 - 519 WP_264676264.1 bestrophin family protein -
LP121_RS09945 (LP121_09860) 2014665..2014877 - 213 WP_264676263.1 bestrophin family protein -
LP121_RS09950 (LP121_09865) 2014874..2015671 - 798 WP_112742207.1 polyphenol oxidase family protein -
LP121_RS09955 (LP121_09870) 2015790..2016839 - 1050 WP_112742206.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226338 WP_112742208.1 NZ_CP087843:c2011707-2011450 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226338 NZ_CP122448:c3901204-3900806 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGAAGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGTGATGCACTCTACGACGACTCGTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGCAGCGCATTTGGTATATTGTCAGGGCGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226338 WP_228157840.1 NZ_CP087843:c2011939-2011697 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226338 NZ_CP122448:c3901500-3901207 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
TGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTTGAAGCATTAATGGACATGCTTG
CAGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCGAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References