Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1985345..1985922 Replicon chromosome
Accession NZ_CP087840
Organism Moraxella bovis strain SAM58116

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP107_RS10025 Protein ID WP_078275234.1
Coordinates 1985345..1985680 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP107_RS10030 Protein ID WP_078275235.1
Coordinates 1985680..1985922 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP107_RS10000 (LP107_09900) 1980685..1980885 + 201 WP_112741955.1 hypothetical protein -
LP107_RS10005 (LP107_09905) 1981045..1981629 + 585 WP_112741954.1 hypothetical protein -
LP107_RS10010 (LP107_09910) 1981794..1983938 + 2145 WP_264676147.1 cation-translocating P-type ATPase -
LP107_RS10015 (LP107_09915) 1984028..1984216 - 189 WP_143821748.1 hypothetical protein -
LP107_RS10020 (LP107_09920) 1984288..1985283 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP107_RS10025 (LP107_09925) 1985345..1985680 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP107_RS10030 (LP107_09930) 1985680..1985922 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP107_RS10035 (LP107_09935) 1986129..1987208 + 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP107_RS10040 (LP107_09940) 1987590..1988312 - 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP107_RS10045 (LP107_09945) 1988501..1989127 + 627 WP_078275237.1 septation protein IspZ -
LP107_RS10050 (LP107_09950) 1989287..1989592 + 306 WP_078275238.1 YciI family protein -
LP107_RS10055 (LP107_09955) 1989601..1990023 + 423 WP_078275239.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226332 WP_078275234.1 NZ_CP087840:c1985680-1985345 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226332 NZ_CP122448:2591229-2592551 [Escherichia coli]
ATGCCTAAACTAGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCTGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGATAGCGTTGGTGCCGTGACGTTAATCCCCGAAGA
TGAAACCGTAACGTGTCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGTTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACTGCGCTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAGGGAATAACGCCAACGACGCACATTATCAAATTGCCGATTGGCGAAAT
CAGACAGCCCAATGCGACGCTCGATCTTAGCCAAAGCGTTGATAATGAGTATTACTGTTTGCTGCTGGCGAAAGAACTCG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAGGGTGCGCGCGTTAGCGGTCAAACGTTTTGACAGGCGTTGG
AATACTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGCCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCCGGTATCGCGCAAATTATGGCTTTTTTAATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAGTTTCAGGTCTTCCAGTGGTTGATTGGCGCAACAGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGGCTCACACCATTTTATGACATCATTTCGGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTCTGGCGACAGCAAAGGTGCTGAAATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCACGGTCGGTTAAGCCGAGAATACGGTATTAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226332 WP_078275235.1 NZ_CP087840:c1985922-1985680 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226332 NZ_CP122448:2590963-2591229 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAACGGCTGGAC
GCAGAGCGAATTGGCGAAAAAAATCGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAATCCTGACAATACCTCGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAAGCA
GCAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References