Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1566641..1567130 Replicon chromosome
Accession NZ_CP087840
Organism Moraxella bovis strain SAM58116

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP107_RS07670 Protein ID WP_112742208.1
Coordinates 1566641..1566898 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP107_RS07675 Protein ID WP_228157840.1
Coordinates 1566888..1567130 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP107_RS07655 (LP107_07580) 1562586..1565108 + 2523 WP_112742210.1 alpha/beta hydrolase -
LP107_RS07660 (LP107_07585) 1565204..1566007 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP107_RS07665 (LP107_07590) 1566073..1566582 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP107_RS07670 (LP107_07595) 1566641..1566898 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP107_RS07675 (LP107_07600) 1566888..1567130 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP107_RS07680 (LP107_07605) 1567175..1567339 + 165 WP_162860378.1 hypothetical protein -
LP107_RS07685 (LP107_07610) 1567421..1567708 - 288 WP_078273310.1 DUF1315 family protein -
LP107_RS07690 (LP107_07615) 1567952..1569185 - 1234 Protein_1495 DUF853 family protein -
LP107_RS07695 (LP107_07620) 1569348..1569866 - 519 WP_264676264.1 bestrophin family protein -
LP107_RS07700 (LP107_07625) 1569856..1570068 - 213 WP_264676263.1 bestrophin family protein -
LP107_RS07705 (LP107_07630) 1570065..1570862 - 798 WP_264676262.1 polyphenol oxidase family protein -
LP107_RS07710 (LP107_07635) 1570981..1572030 - 1050 WP_264676261.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226329 WP_112742208.1 NZ_CP087840:c1566898-1566641 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226329 NZ_CP122448:2009538-2009792 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226329 WP_228157840.1 NZ_CP087840:c1567130-1566888 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226329 NZ_CP122448:2009290-2009541 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References