Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafQ-RelB |
| Location | 434901..435459 | Replicon | chromosome |
| Accession | NZ_CP087840 | ||
| Organism | Moraxella bovis strain SAM58116 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LP107_RS02190 | Protein ID | WP_228157760.1 |
| Coordinates | 435187..435459 (+) | Length | 91 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A1S9ZVK6 |
| Locus tag | LP107_RS02185 | Protein ID | WP_029103533.1 |
| Coordinates | 434901..435194 (+) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LP107_RS02165 (LP107_02155) | 430412..431746 | - | 1335 | WP_078275195.1 | valine--pyruvate transaminase | - |
| LP107_RS02170 (LP107_02160) | 431866..432477 | + | 612 | WP_112741794.1 | methyltransferase | - |
| LP107_RS02175 (LP107_02165) | 432498..433214 | + | 717 | WP_078275193.1 | hypothetical protein | - |
| LP107_RS02180 (LP107_02170) | 433423..434757 | + | 1335 | WP_112741795.1 | deoxyguanosinetriphosphate triphosphohydrolase | - |
| LP107_RS02185 (LP107_02175) | 434901..435194 | + | 294 | WP_029103533.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LP107_RS02190 (LP107_02180) | 435187..435459 | + | 273 | WP_228157760.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| LP107_RS02195 (LP107_02185) | 435524..435979 | - | 456 | WP_264675985.1 | type IV secretion protein Rhs | - |
| LP107_RS02200 (LP107_02190) | 436064..436441 | + | 378 | WP_264675984.1 | hypothetical protein | - |
| LP107_RS02205 (LP107_02195) | 436799..438058 | + | 1260 | WP_264675983.1 | replication-associated recombination protein A | - |
| LP107_RS02210 (LP107_02200) | 438138..438401 | + | 264 | WP_264675982.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| LP107_RS02215 (LP107_02205) | 438398..438790 | + | 393 | WP_078275188.1 | type II toxin-antitoxin system VapC family toxin | - |
| LP107_RS02220 (LP107_02210) | 438913..439443 | + | 531 | WP_078275187.1 | HI_0552 family protein | - |
| LP107_RS02225 (LP107_02215) | 439440..440006 | - | 567 | WP_078275186.1 | hypothetical protein | - |
| LP107_RS02230 (LP107_02220) | 440009..440245 | - | 237 | WP_078275185.1 | sulfurtransferase TusA | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10415.99 Da Isoelectric Point: 6.9668
>T226325 WP_228157760.1 NZ_CP087840:435187-435459 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
Download Length: 273 bp
>T226325 NZ_CP122448:c850055-849681 [Escherichia coli]
ATGAAAACATTACCCGATACACACGTACGGGAGGCATCGAGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTACTGGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACTTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGAAACGATGA
ATGAAAACATTACCCGATACACACGTACGGGAGGCATCGAGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTACTGGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACTTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGAAACGATGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 11068.31 Da Isoelectric Point: 4.7769
>AT226325 WP_029103533.1 NZ_CP087840:434901-435194 [Moraxella bovis]
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
Download Length: 294 bp
>AT226325 NZ_CP122448:c850513-850145 [Escherichia coli]
GTGTCAGACGCACTCTCCGGGACAATGCTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACAGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGTCTGACCTGCAAAGCTGACACTCTCGGTAGCGG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA
GTGTCAGACGCACTCTCCGGGACAATGCTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACAGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGTCTGACCTGCAAAGCTGACACTCTCGGTAGCGG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|