Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1975202..1975779 Replicon chromosome
Accession NZ_CP087837
Organism Moraxella bovis strain SAM68509

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP086_RS09955 Protein ID WP_078275234.1
Coordinates 1975202..1975537 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP086_RS09960 Protein ID WP_078275235.1
Coordinates 1975537..1975779 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP086_RS09930 (LP086_09840) 1970542..1970742 + 201 WP_112741955.1 hypothetical protein -
LP086_RS09935 (LP086_09845) 1970902..1971486 + 585 WP_112741954.1 hypothetical protein -
LP086_RS09940 (LP086_09850) 1971651..1973795 + 2145 WP_264676147.1 cation-translocating P-type ATPase -
LP086_RS09945 (LP086_09855) 1973885..1974073 - 189 WP_143821748.1 hypothetical protein -
LP086_RS09950 (LP086_09860) 1974145..1975140 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP086_RS09955 (LP086_09865) 1975202..1975537 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP086_RS09960 (LP086_09870) 1975537..1975779 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP086_RS09965 (LP086_09875) 1975986..1977065 + 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP086_RS09970 (LP086_09880) 1977447..1978169 - 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP086_RS09975 (LP086_09885) 1978358..1978984 + 627 WP_078275237.1 septation protein IspZ -
LP086_RS09980 (LP086_09890) 1979144..1979449 + 306 WP_078275238.1 YciI family protein -
LP086_RS09985 (LP086_09895) 1979458..1979880 + 423 WP_078275239.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226321 WP_078275234.1 NZ_CP087837:c1975537-1975202 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226321 NZ_CP122443:43057-43362 [Enterobacter ludwigii]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTTTCCCGTGAACTCTATCCGGTGG
TGCACATCGGGGACGAAAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACTTCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226321 WP_078275235.1 NZ_CP087837:c1975779-1975537 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226321 NZ_CP122443:42837-43055 [Enterobacter ludwigii]
ATGAAGCAGCGCATCACTGTCACCATAGACAGCGACAGTTATCAGTTACTGAAATCCGCAGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTTCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGATTTATTGAGATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References