Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1566345..1566834 Replicon chromosome
Accession NZ_CP087837
Organism Moraxella bovis strain SAM68509

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP086_RS07695 Protein ID WP_112742208.1
Coordinates 1566345..1566602 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP086_RS07700 Protein ID WP_228157840.1
Coordinates 1566592..1566834 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP086_RS07680 (LP086_07605) 1562290..1564812 + 2523 WP_112742210.1 alpha/beta hydrolase -
LP086_RS07685 (LP086_07610) 1564908..1565711 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP086_RS07690 (LP086_07615) 1565777..1566286 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP086_RS07695 (LP086_07620) 1566345..1566602 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP086_RS07700 (LP086_07625) 1566592..1566834 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP086_RS07705 (LP086_07630) 1566879..1567043 + 165 WP_162860378.1 hypothetical protein -
LP086_RS07710 (LP086_07635) 1567125..1567412 - 288 WP_078273310.1 DUF1315 family protein -
LP086_RS07715 (LP086_07640) 1567656..1568889 - 1234 Protein_1503 DUF853 family protein -
LP086_RS07720 (LP086_07645) 1569052..1569570 - 519 WP_264676264.1 bestrophin family protein -
LP086_RS07725 (LP086_07650) 1569560..1569772 - 213 WP_264676263.1 bestrophin family protein -
LP086_RS07730 (LP086_07655) 1569769..1570566 - 798 WP_264676262.1 polyphenol oxidase family protein -
LP086_RS07735 (LP086_07660) 1570685..1571734 - 1050 WP_264676261.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226318 WP_112742208.1 NZ_CP087837:c1566602-1566345 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226318 NZ_CP122442:c3827018-3826779 [Enterobacter ludwigii]
ATGACTTATGAACTCGTATTTGATCCGAGGGCGTTCAAGGAGTGGACCAGGCTGGGTGATACCGTAAAAAATCAGTTTAA
GAAGAAGCTTGCGAACGTGTTGGTGAACCCCAGGGTTGAATCGGCTCGCCTGCATGGCCTGCCTGATTGCGACAAGATAA
AACTCAGATCCCAGGGTTATCGTTTGGTCTATCAGGTTCAGGACAACGTTGTGACGGTATGTGTTATTGCTATCGGTTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226318 WP_228157840.1 NZ_CP087837:c1566834-1566592 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226318 NZ_CP122442:c3827250-3827008 [Enterobacter ludwigii]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAACGAGGCTTATGCCGTGCTTGAAAAACTCAATATCACGCC
AACGGAAGCCGTTCGGTTACTGTTTCAGTACGTTGCGGAGACGGGGCGTATGCCGGTGAAAACGGTCACTGTTAGCGACA
GTGAAGATGAACTCATACAGACAGTCCGGGAGCGGTTGGCTAATCCGCAAAAAGGAATTAAGGTTAGGCTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References