Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 677143..677719 Replicon chromosome
Accession NZ_CP087837
Organism Moraxella bovis strain SAM68509

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag LP086_RS03490 Protein ID WP_264676341.1
Coordinates 677459..677719 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag LP086_RS03485 Protein ID WP_078273964.1
Coordinates 677143..677478 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP086_RS03465 (LP086_03435) 672304..673386 - 1083 WP_078273961.1 tRNA pseudouridine(13) synthase TruD -
LP086_RS03470 (LP086_03440) 673520..674287 - 768 WP_112742541.1 carbonic anhydrase family protein -
LP086_RS03475 (LP086_03445) 674932..676113 - 1182 WP_078274027.1 fatty acid desaturase -
LP086_RS03480 (LP086_03450) 676375..676959 + 585 Protein_671 TetR/AcrR family transcriptional regulator -
LP086_RS03485 (LP086_03455) 677143..677478 - 336 WP_078273964.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
LP086_RS03490 (LP086_03460) 677459..677719 - 261 WP_264676341.1 type II toxin-antitoxin system HicA family toxin Toxin
LP086_RS03495 (LP086_03465) 677918..678625 + 708 WP_264675942.1 ParA family protein -
LP086_RS03500 (LP086_03470) 678715..680100 - 1386 WP_078273966.1 APC family permease -
LP086_RS03505 (LP086_03475) 680613..682688 - 2076 WP_264675941.1 NAD-dependent DNA ligase LigA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Uncharacterised protein family HicB

(54-104)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9551.46 Da        Isoelectric Point: 4.3376

>T226316 WP_264676341.1 NZ_CP087837:c677719-677459 [Moraxella bovis]
IEALFVALGADISERAGSRMAVALNGQVMVFHRPHPSPNTDKSAVMSIRKWLDGMGITPLDDDSQTDEYADKQTDEQEQT
HEHNDN

Download         Length: 261 bp

>T226316 NZ_CP122442:c2318791-2318688 [Enterobacter ludwigii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12189.67 Da        Isoelectric Point: 4.5658

>AT226316 WP_078273964.1 NZ_CP087837:c677478-677143 [Moraxella bovis]
MNTMTINNHKALITFDSELGLFRGEFIGLNGGADFYADSVDGLNEQGALSLQAFLDVCQEQGISPYQSYSGKFVTRLPKE
LHQKIAETATAKGISLNQWINETLSREVGFA

Download         Length: 336 bp

>AT226316 NZ_CP122442:2318674-2318826 [Enterobacter ludwigii]
GCTTTCAATCAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCG
CTAAAAGTTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References