Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafQ-RelB |
| Location | 435206..435764 | Replicon | chromosome |
| Accession | NZ_CP087837 | ||
| Organism | Moraxella bovis strain SAM68509 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LP086_RS02200 | Protein ID | WP_228157760.1 |
| Coordinates | 435492..435764 (+) | Length | 91 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A1S9ZVK6 |
| Locus tag | LP086_RS02195 | Protein ID | WP_029103533.1 |
| Coordinates | 435206..435499 (+) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LP086_RS02175 (LP086_02165) | 430717..432051 | - | 1335 | WP_078275195.1 | valine--pyruvate transaminase | - |
| LP086_RS02180 (LP086_02170) | 432171..432782 | + | 612 | WP_112741794.1 | methyltransferase | - |
| LP086_RS02185 (LP086_02175) | 432803..433519 | + | 717 | WP_078275193.1 | hypothetical protein | - |
| LP086_RS02190 (LP086_02180) | 433728..435062 | + | 1335 | WP_112741795.1 | deoxyguanosinetriphosphate triphosphohydrolase | - |
| LP086_RS02195 (LP086_02185) | 435206..435499 | + | 294 | WP_029103533.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LP086_RS02200 (LP086_02190) | 435492..435764 | + | 273 | WP_228157760.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| LP086_RS02205 (LP086_02195) | 435829..436284 | - | 456 | WP_264675985.1 | type IV secretion protein Rhs | - |
| LP086_RS02210 (LP086_02200) | 436369..436746 | + | 378 | WP_264675984.1 | hypothetical protein | - |
| LP086_RS02215 (LP086_02205) | 437104..438363 | + | 1260 | WP_264675983.1 | replication-associated recombination protein A | - |
| LP086_RS02220 (LP086_02210) | 438443..438706 | + | 264 | WP_264675982.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| LP086_RS02225 (LP086_02215) | 438703..439095 | + | 393 | WP_078275188.1 | type II toxin-antitoxin system VapC family toxin | - |
| LP086_RS02230 (LP086_02220) | 439218..439748 | + | 531 | WP_078275187.1 | HI_0552 family protein | - |
| LP086_RS02235 (LP086_02225) | 439745..440311 | - | 567 | WP_078275186.1 | hypothetical protein | - |
| LP086_RS02240 (LP086_02230) | 440314..440550 | - | 237 | WP_078275185.1 | sulfurtransferase TusA | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | katA | 378493..438363 | 59870 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10415.99 Da Isoelectric Point: 6.9668
>T226314 WP_228157760.1 NZ_CP087837:435492-435764 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
Download Length: 273 bp
>T226314 NZ_CP122442:594504-594989 [Enterobacter ludwigii]
GTGGGACGTGTAACAGCACCAGAACCATTATCCAGCTCCCATCAACTAGCAGAGTTCGTCAGTGGTGAGGCAGTACTTGA
TGACTGGCTTAAACAGAGGGGATTAAAAAACCAAGCTCTTGGTGCAGCACGAACGTTCGTCGTTTGTAAAAGAGACACTA
AACAGGTTGTCGGTTTTTACTCTCTGGCCACCGGCAGCGTTAACCACGTGGAAGCAATGGGAAGCCTCAGGCGCAATATG
CCAGATCCAATTCCCGTAATCATACTTGCTCGCCTGGCAGTTGATGTTTCATACCGTGGCCAAGGGCTCGGGGCCGATTT
ACTGCATGATGCAGTTCTGCGCTGTTACCGTGTAGCTGAGAATATTGGAGTCCGTGCGATTATGGTTCATGCACTGACTG
AAGAAGCCAAAAACTTTTATCTTCACCATGGCTTTAAGGCATCACAAACTCAGGAACGGACATTGTTTTTAAAGTTACCA
CAGTGA
GTGGGACGTGTAACAGCACCAGAACCATTATCCAGCTCCCATCAACTAGCAGAGTTCGTCAGTGGTGAGGCAGTACTTGA
TGACTGGCTTAAACAGAGGGGATTAAAAAACCAAGCTCTTGGTGCAGCACGAACGTTCGTCGTTTGTAAAAGAGACACTA
AACAGGTTGTCGGTTTTTACTCTCTGGCCACCGGCAGCGTTAACCACGTGGAAGCAATGGGAAGCCTCAGGCGCAATATG
CCAGATCCAATTCCCGTAATCATACTTGCTCGCCTGGCAGTTGATGTTTCATACCGTGGCCAAGGGCTCGGGGCCGATTT
ACTGCATGATGCAGTTCTGCGCTGTTACCGTGTAGCTGAGAATATTGGAGTCCGTGCGATTATGGTTCATGCACTGACTG
AAGAAGCCAAAAACTTTTATCTTCACCATGGCTTTAAGGCATCACAAACTCAGGAACGGACATTGTTTTTAAAGTTACCA
CAGTGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 11068.31 Da Isoelectric Point: 4.7769
>AT226314 WP_029103533.1 NZ_CP087837:435206-435499 [Moraxella bovis]
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
Download Length: 294 bp
>AT226314 NZ_CP122442:594250-594516 [Enterobacter ludwigii]
ATGAAATCAGATGTTCAGCTCAACCTTAGAGCTAAAGAATCTCAAAGAGCACTTATTGATGCTGCAGCAGAGATTCTCCA
TAAATCACGCACGGACTTCATCCTGGAAATGGCATGTCAGGCTGCGGAGAATGTGATCCTCGATCGTCGCGTATTTAATT
TTAACGATGAGCAGTATGCAGAGTTTATCGATATGCTCGATGCACCGGTTTCGGATGAGGCGGCTATTGATAAACTTCTG
GCAAGGAAACCTCAGTGGGACGTGTAA
ATGAAATCAGATGTTCAGCTCAACCTTAGAGCTAAAGAATCTCAAAGAGCACTTATTGATGCTGCAGCAGAGATTCTCCA
TAAATCACGCACGGACTTCATCCTGGAAATGGCATGTCAGGCTGCGGAGAATGTGATCCTCGATCGTCGCGTATTTAATT
TTAACGATGAGCAGTATGCAGAGTTTATCGATATGCTCGATGCACCGGTTTCGGATGAGGCGGCTATTGATAAACTTCTG
GCAAGGAAACCTCAGTGGGACGTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|