Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1249932..1250421 Replicon chromosome
Accession NZ_CP087830
Organism Moraxella bovis strain SAM102599

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP092_RS06620 Protein ID WP_112742208.1
Coordinates 1250164..1250421 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP092_RS06615 Protein ID WP_228157840.1
Coordinates 1249932..1250174 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP092_RS06580 (LP092_06530) 1245032..1246081 + 1050 WP_112742206.1 RluA family pseudouridine synthase -
LP092_RS06585 (LP092_06535) 1246200..1246997 + 798 WP_112742207.1 polyphenol oxidase family protein -
LP092_RS06590 1246994..1247206 + 213 WP_264676263.1 bestrophin family protein -
LP092_RS06595 (LP092_06540) 1247196..1247714 + 519 WP_264676264.1 bestrophin family protein -
LP092_RS06600 (LP092_06545) 1247877..1249110 + 1234 Protein_1290 DUF853 family protein -
LP092_RS06605 (LP092_06550) 1249354..1249641 + 288 WP_078273310.1 DUF1315 family protein -
LP092_RS06610 (LP092_06555) 1249723..1249887 - 165 WP_162860378.1 hypothetical protein -
LP092_RS06615 (LP092_06560) 1249932..1250174 + 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP092_RS06620 (LP092_06565) 1250164..1250421 + 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP092_RS06625 (LP092_06570) 1250480..1250989 + 510 WP_112742209.1 peptidylprolyl isomerase -
LP092_RS06630 (LP092_06575) 1251055..1251858 + 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP092_RS06635 (LP092_06580) 1251954..1254476 - 2523 WP_112742210.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226306 WP_112742208.1 NZ_CP087830:1250164-1250421 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226306 NZ_CP122407:c4280007-4279594 [Rugamonas sp. DEMB1]
TTGAGCTATCTGCTCGACACCAACGTCCTGTCGGAGTTGCGCCGTAAGATGCCCAACAGTGTTGTCCTCGACTGGATGGC
CCGGCGGCCGGCGGCCACCCTGTATTTGAGCGTGTTGACACTCGGTGAGCTACGCAAGGGCGTTGAAGGAGTGAACGATC
CAATTCGTCGCGCGAACTTGCTTGACTGGTTGGAGAACGAGTTGCCGGCCTTTTTCGCCGGACGCATTCTTGCAGTCGAC
GCCCAGGTGGCAGATCGCTGGGGGCGCATGGTGGCGGCGGCGGGGCGTCCCGTGCCAGCCATTGACAGCTTGATCGGCGC
AACCGCAGCACATTACGGTTTGAGCCTGGTAACGCGCAACGCGCGTGATTTCACGGACCTGGGGCTGGATGTGATCAACC
CCTGGACTCCCTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226306 WP_228157840.1 NZ_CP087830:1249932-1250174 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226306 NZ_CP122407:c4280255-4280004 [Rugamonas sp. DEMB1]
ATGCAAACATGGCAGATGCAAGAGGCGAAGGCGCGGTTGTCCGAACTGGTGAAGCTCGCGCAGACGGAGGGGCCACAGGA
CATTACCCTACACGGGCGGTCGGTGGCGGTGGTGTTGTCGCGCGAGGCGTTCGAGCGCTTGTCGGGCAGCAAACAGTCTT
TGGTGGAGTTCATGCGCCAGTCGCCCCTCTATGACCTGGAGGAGATCGAGTTCGAGCGCGACCGCAGTACGACCCGCGAG
ACCCCACTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References