Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 822670..823247 Replicon chromosome
Accession NZ_CP087830
Organism Moraxella bovis strain SAM102599

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP092_RS04255 Protein ID WP_078275234.1
Coordinates 822912..823247 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP092_RS04250 Protein ID WP_078275235.1
Coordinates 822670..822912 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP092_RS04225 (LP092_04200) 818569..818991 - 423 WP_078275239.1 hypothetical protein -
LP092_RS04230 (LP092_04205) 819000..819305 - 306 WP_078275238.1 YciI family protein -
LP092_RS04235 (LP092_04210) 819465..820091 - 627 WP_078275237.1 septation protein IspZ -
LP092_RS04240 (LP092_04215) 820280..821002 + 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP092_RS04245 (LP092_04220) 821384..822463 - 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP092_RS04250 (LP092_04225) 822670..822912 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP092_RS04255 (LP092_04230) 822912..823247 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP092_RS04260 (LP092_04235) 823309..824304 + 996 WP_208624081.1 polyprenyl synthetase family protein -
LP092_RS04265 (LP092_04240) 824376..824564 + 189 WP_143821748.1 hypothetical protein -
LP092_RS04270 (LP092_04245) 824654..826798 - 2145 WP_264676147.1 cation-translocating P-type ATPase -
LP092_RS04275 (LP092_04250) 826963..827493 - 531 WP_264684205.1 hypothetical protein -
LP092_RS04280 (LP092_04255) 827707..827907 - 201 WP_112741955.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226303 WP_078275234.1 NZ_CP087830:822912-823247 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226303 NZ_CP122407:2722958-2723233 [Rugamonas sp. DEMB1]
ATGGACTTGCGCTGGACCAGCAAGGCACTCTCCGATTTGATACGGCTGCATGAGTTCTTGGCGACGGTGAACAAGCCGGC
CGCTGCCCGTGCCGTGCAGTCGCTCACGGCCGCCGCCGCCAGTTTGCTGGCGAATCCACGCATAGGCGAACGGTTGGAGG
AATTCGACCCACGCGACATCCGCCGCATCCTGGTTGGCCGCTACGAGCTGCGCTATGAGATCGAGGCGTCAACGATTTAC
CTCTTGCGGCTGTGGCACACGCGTGAAGACCGCTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226303 WP_078275235.1 NZ_CP087830:822670-822912 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226303 NZ_CP122407:2722683-2722958 [Rugamonas sp. DEMB1]
ATGGCACAGACGGAAACCAAAGTGATTACCGCACATATCCCTTTGCCGCTGGCCGACAAAGTCGATCAATTGGCATCCCG
GCTCGAGCGTTCGCGCGGCTGGATCGTTAAACAGGCGCTCAGCGCTTGGGTTGACCAAGAAGAGGAGCGCAGTCGCCTCA
CGCGCGAAGCGATGGCCGATGTGGCCGCCGGGCGTGTCATCGATCATCAGTCGGTGCAGGCGTGGGCAGACAGCCTTGGC
ACCGACAGGCCGCTGGCCGCGCCGGTGCTGCCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References