Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2004379..2004956 Replicon chromosome
Accession NZ_CP087828
Organism Moraxella bovis strain SAM102600

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP099_RS10110 Protein ID WP_078275234.1
Coordinates 2004379..2004714 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP099_RS10115 Protein ID WP_078275235.1
Coordinates 2004714..2004956 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP099_RS10085 (LP099_09990) 1999720..1999920 + 201 WP_112741955.1 hypothetical protein -
LP099_RS10090 (LP099_09995) 2000079..2000663 + 585 WP_112741954.1 hypothetical protein -
LP099_RS10095 (LP099_10000) 2000828..2002972 + 2145 WP_264684206.1 cation-translocating P-type ATPase -
LP099_RS10100 (LP099_10005) 2003062..2003250 - 189 WP_143821748.1 hypothetical protein -
LP099_RS10105 (LP099_10010) 2003322..2004317 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP099_RS10110 (LP099_10015) 2004379..2004714 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP099_RS10115 (LP099_10020) 2004714..2004956 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP099_RS10120 (LP099_10025) 2005163..2006242 + 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP099_RS10125 (LP099_10030) 2006624..2007346 - 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP099_RS10130 (LP099_10035) 2007535..2008161 + 627 WP_078275237.1 septation protein IspZ -
LP099_RS10135 (LP099_10040) 2008321..2008626 + 306 WP_078275238.1 YciI family protein -
LP099_RS10140 (LP099_10045) 2008635..2009057 + 423 WP_078275239.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226299 WP_078275234.1 NZ_CP087828:c2004714-2004379 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226299 NZ_CP122407:363133-363429 [Rugamonas sp. DEMB1]
ATGGAGAAGATCTCGCCCCATTACAGCTTGCCAAAGGTGAAGGCCCTCATTGACGAGGGCCGGGTGGCGTCGACCTTTTC
CGCGTTGACGGGCGCTGCGGCATTGGGTATCGACTTCGCGGGGATGGTCGCTATTGTTAAGGCGCTGACTAGGCGCGACT
TCTACAAAAGCATGACCTCGCGTGCCGACCACCACATCTGGCAAGACGTGTACCGTCCAAGCACCCCGGTCGGCAAGGTC
TATCTAAAACTCACTGTCGTTGACGGCGTGTTGATCGTCTCGTTCAAGGAGCTGTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226299 WP_078275235.1 NZ_CP087828:c2004956-2004714 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226299 NZ_CP122407:363431-363670 [Rugamonas sp. DEMB1]
ATGAAATGTCCTGTTTGCGCAGCGGCCGAGCTGGTGCGGGACTGCCGCGATCTGCCCCATGCCTACAAAGGCGCAAGCAC
GATGATTGCCGCCGTCTGCGGCGATTACTGTCCCGCTTGCGGCGAAAGCGTGCTCGACGCGAAAGAGTCGTCGCGTGTCA
GCGCGGCGATGCTGGCCTTCCATCGACAGGTCGAGGCGGCGAATCGCGAAGCGGATCATATTGTTGGAACGCCGCCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References