Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 428508..429066 Replicon chromosome
Accession NZ_CP087828
Organism Moraxella bovis strain SAM102600

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP099_RS02150 Protein ID WP_228157760.1
Coordinates 428794..429066 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1S9ZVK6
Locus tag LP099_RS02145 Protein ID WP_029103533.1
Coordinates 428508..428801 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP099_RS02125 (LP099_02110) 424019..425353 - 1335 WP_078275195.1 valine--pyruvate transaminase -
LP099_RS02130 (LP099_02115) 425473..426084 + 612 WP_112741794.1 methyltransferase -
LP099_RS02135 (LP099_02120) 426105..426821 + 717 WP_078275193.1 hypothetical protein -
LP099_RS02140 (LP099_02125) 427030..428364 + 1335 WP_112741795.1 deoxyguanosinetriphosphate triphosphohydrolase -
LP099_RS02145 (LP099_02130) 428508..428801 + 294 WP_029103533.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP099_RS02150 (LP099_02135) 428794..429066 + 273 WP_228157760.1 type II toxin-antitoxin system YafQ family toxin Toxin
LP099_RS02155 (LP099_02140) 429131..429571 - 441 WP_208624064.1 type IV secretion protein Rhs -
LP099_RS02160 (LP099_02145) 429622..430395 + 774 WP_078275191.1 hypothetical protein -
LP099_RS02165 (LP099_02150) 430374..431633 + 1260 WP_078275190.1 replication-associated recombination protein A -
LP099_RS02170 (LP099_02155) 431713..431976 + 264 WP_078275189.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
LP099_RS02175 (LP099_02160) 431973..432365 + 393 WP_078275188.1 type II toxin-antitoxin system VapC family toxin -
LP099_RS02180 (LP099_02165) 432488..433018 + 531 WP_078275187.1 HI_0552 family protein -
LP099_RS02185 (LP099_02170) 433015..433581 - 567 WP_078275186.1 hypothetical protein -
LP099_RS02190 (LP099_02175) 433584..433820 - 237 WP_078275185.1 sulfurtransferase TusA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-67)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10415.99 Da        Isoelectric Point: 6.9668

>T226294 WP_228157760.1 NZ_CP087828:428794-429066 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG

Download         Length: 273 bp

>T226294 NZ_CP122401:271020-271123 [Enterobacter roggenkampii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11068.31 Da        Isoelectric Point: 4.7769

>AT226294 WP_029103533.1 NZ_CP087828:428508-428801 [Moraxella bovis]
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG

Download         Length: 294 bp

>AT226294 NZ_CP122401:c271128-270985 [Enterobacter roggenkampii]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1S9ZVK6

References