Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafQ-RelB |
| Location | 2772542..2773100 | Replicon | chromosome |
| Accession | NZ_CP087825 | ||
| Organism | Moraxella bovis strain SAM102601 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LP108_RS14060 | Protein ID | WP_228157760.1 |
| Coordinates | 2772828..2773100 (+) | Length | 91 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A1S9ZVK6 |
| Locus tag | LP108_RS14055 | Protein ID | WP_029103533.1 |
| Coordinates | 2772542..2772835 (+) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LP108_RS14035 (LP108_13895) | 2768053..2769387 | - | 1335 | WP_078275195.1 | valine--pyruvate transaminase | - |
| LP108_RS14040 (LP108_13900) | 2769507..2770118 | + | 612 | WP_112741794.1 | methyltransferase | - |
| LP108_RS14045 (LP108_13905) | 2770139..2770855 | + | 717 | WP_078275193.1 | hypothetical protein | - |
| LP108_RS14050 (LP108_13910) | 2771064..2772398 | + | 1335 | WP_112741795.1 | deoxyguanosinetriphosphate triphosphohydrolase | - |
| LP108_RS14055 (LP108_13915) | 2772542..2772835 | + | 294 | WP_029103533.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LP108_RS14060 (LP108_13920) | 2772828..2773100 | + | 273 | WP_228157760.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| LP108_RS14065 (LP108_13925) | 2773165..2773620 | - | 456 | WP_264675985.1 | type IV secretion protein Rhs | - |
| LP108_RS14070 (LP108_13930) | 2773705..2774082 | + | 378 | WP_264675984.1 | hypothetical protein | - |
| LP108_RS14075 (LP108_13935) | 2774440..2775699 | + | 1260 | WP_264675983.1 | replication-associated recombination protein A | - |
| LP108_RS14080 (LP108_13940) | 2775779..2776042 | + | 264 | WP_264675982.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| LP108_RS14085 (LP108_13945) | 2776039..2776431 | + | 393 | WP_078275188.1 | type II toxin-antitoxin system VapC family toxin | - |
| LP108_RS14090 (LP108_13950) | 2776554..2777084 | + | 531 | WP_078275187.1 | HI_0552 family protein | - |
| LP108_RS14095 (LP108_13955) | 2777081..2777647 | - | 567 | WP_078275186.1 | hypothetical protein | - |
| LP108_RS14100 (LP108_13960) | 2777650..2777886 | - | 237 | WP_078275185.1 | sulfurtransferase TusA | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10415.99 Da Isoelectric Point: 6.9668
>T226291 WP_228157760.1 NZ_CP087825:2772828-2773100 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
Download Length: 273 bp
>T226291 NZ_CP122391:c43664-43182 [Klebsiella pneumoniae]
GTGGGATGTATAACTGCGCCCGAGCCGTTATCCAGCGCCCATCAACTGGCAGAGTTCGTCAGTGGGGAAACGGTACTCGA
TGAATGGTTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCACGAACTTTCGTTGTTTGCAAGACGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGCAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTTTCATTGCACGGAAAAGGGGTTGGCGCCGATTT
ACTTCACGATGCGGTTCTACGCTGTTATCGCGTAGCTGAGAATATTGGCGTTCGTGCGATAATGGTTCACGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCGCAAACTTATGAGCGGACTCTGTTCCTTAAACTTCCA
TGA
GTGGGATGTATAACTGCGCCCGAGCCGTTATCCAGCGCCCATCAACTGGCAGAGTTCGTCAGTGGGGAAACGGTACTCGA
TGAATGGTTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCACGAACTTTCGTTGTTTGCAAGACGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGCAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTTTCATTGCACGGAAAAGGGGTTGGCGCCGATTT
ACTTCACGATGCGGTTCTACGCTGTTATCGCGTAGCTGAGAATATTGGCGTTCGTGCGATAATGGTTCACGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCGCAAACTTATGAGCGGACTCTGTTCCTTAAACTTCCA
TGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 11068.31 Da Isoelectric Point: 4.7769
>AT226291 WP_029103533.1 NZ_CP087825:2772542-2772835 [Moraxella bovis]
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
Download Length: 294 bp
>AT226291 NZ_CP122391:c43918-43652 [Klebsiella pneumoniae]
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGGGCACTCATCGATGCCGCTGCAGAAATCCTTCA
TAAATCGCGAACCGACTTCATTCTTGAGATGGCCTGCAAGGCTGCGGAGAACGTGATCCTTGATCGTCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGAGCCTGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGATGTATAA
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGGGCACTCATCGATGCCGCTGCAGAAATCCTTCA
TAAATCGCGAACCGACTTCATTCTTGAGATGGCCTGCAAGGCTGCGGAGAACGTGATCCTTGATCGTCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGAGCCTGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGATGTATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|