Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1512080..1512657 Replicon chromosome
Accession NZ_CP087825
Organism Moraxella bovis strain SAM102601

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP108_RS07580 Protein ID WP_078275234.1
Coordinates 1512080..1512415 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP108_RS07585 Protein ID WP_078275235.1
Coordinates 1512415..1512657 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP108_RS07555 (LP108_07465) 1507420..1507620 + 201 WP_112741955.1 hypothetical protein -
LP108_RS07560 (LP108_07470) 1507780..1508364 + 585 WP_112741954.1 hypothetical protein -
LP108_RS07565 (LP108_07475) 1508529..1510673 + 2145 WP_264676147.1 cation-translocating P-type ATPase -
LP108_RS07570 (LP108_07480) 1510763..1510951 - 189 WP_143821748.1 hypothetical protein -
LP108_RS07575 (LP108_07485) 1511023..1512018 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP108_RS07580 (LP108_07490) 1512080..1512415 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP108_RS07585 (LP108_07495) 1512415..1512657 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP108_RS07590 (LP108_07500) 1512864..1513943 + 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP108_RS07595 (LP108_07505) 1514325..1515047 - 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP108_RS07600 (LP108_07510) 1515236..1515862 + 627 WP_078275237.1 septation protein IspZ -
LP108_RS07605 (LP108_07515) 1516022..1516327 + 306 WP_078275238.1 YciI family protein -
LP108_RS07610 (LP108_07520) 1516336..1516758 + 423 WP_078275239.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226287 WP_078275234.1 NZ_CP087825:c1512415-1512080 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226287 NZ_CP122389:c4829061-4828777 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGACCAGGCTGAGCGATTTACCTGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226287 WP_078275235.1 NZ_CP087825:c1512657-1512415 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226287 NZ_CP122389:c4829293-4829051 [Klebsiella pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCGGGGGTTAAGGTGAGTCTGGATGACCTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References