Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1109799..1110288 Replicon chromosome
Accession NZ_CP087825
Organism Moraxella bovis strain SAM102601

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP108_RS05390 Protein ID WP_112742208.1
Coordinates 1109799..1110056 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP108_RS05395 Protein ID WP_228157840.1
Coordinates 1110046..1110288 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP108_RS05375 (LP108_05300) 1105744..1108266 + 2523 WP_112742210.1 alpha/beta hydrolase -
LP108_RS05380 (LP108_05305) 1108362..1109165 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP108_RS05385 (LP108_05310) 1109231..1109740 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP108_RS05390 (LP108_05315) 1109799..1110056 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP108_RS05395 (LP108_05320) 1110046..1110288 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP108_RS05400 (LP108_05325) 1110333..1110497 + 165 WP_162860378.1 hypothetical protein -
LP108_RS05405 (LP108_05330) 1110579..1110866 - 288 WP_078273310.1 DUF1315 family protein -
LP108_RS05410 (LP108_05335) 1111110..1112343 - 1234 Protein_1060 DUF853 family protein -
LP108_RS05415 (LP108_05340) 1112506..1113024 - 519 WP_264676264.1 bestrophin family protein -
LP108_RS05420 (LP108_05345) 1113014..1113226 - 213 WP_264676263.1 bestrophin family protein -
LP108_RS05425 (LP108_05350) 1113223..1114020 - 798 WP_112742207.1 polyphenol oxidase family protein -
LP108_RS05430 (LP108_05355) 1114139..1115188 - 1050 WP_112742206.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226284 WP_112742208.1 NZ_CP087825:c1110056-1109799 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226284 NZ_CP122389:4097528-4097746 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATTCCGACCTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226284 WP_228157840.1 NZ_CP087825:c1110288-1110046 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226284 NZ_CP122389:4097127-4097501 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References