Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 833114..833691 Replicon chromosome
Accession NZ_CP087823
Organism Moraxella bovis strain SAM102602

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP123_RS04320 Protein ID WP_078275234.1
Coordinates 833356..833691 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP123_RS04315 Protein ID WP_078275235.1
Coordinates 833114..833356 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP123_RS04290 (LP123_04265) 829013..829435 - 423 WP_078275239.1 hypothetical protein -
LP123_RS04295 (LP123_04270) 829444..829749 - 306 WP_078275238.1 YciI family protein -
LP123_RS04300 (LP123_04275) 829909..830535 - 627 WP_078275237.1 septation protein IspZ -
LP123_RS04305 (LP123_04280) 830724..831446 + 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP123_RS04310 (LP123_04285) 831828..832907 - 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP123_RS04315 (LP123_04290) 833114..833356 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP123_RS04320 (LP123_04295) 833356..833691 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP123_RS04325 (LP123_04300) 833753..834748 + 996 WP_208624081.1 polyprenyl synthetase family protein -
LP123_RS04330 (LP123_04305) 834820..835008 + 189 WP_143821748.1 hypothetical protein -
LP123_RS04335 (LP123_04310) 835098..837242 - 2145 WP_264684206.1 cation-translocating P-type ATPase -
LP123_RS04340 (LP123_04315) 837407..837991 - 585 WP_112741954.1 hypothetical protein -
LP123_RS04345 (LP123_04320) 838150..838350 - 201 WP_112741955.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226275 WP_078275234.1 NZ_CP087823:833356-833691 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226275 NZ_CP122379:3187941-3188243 [Aequorivita sp. Ant34-E75]
ATGATAATTACCGAAAAAACATCTGAATTCGATAAGTGGATTAGAAAGCTAAAAGACATTCGGGCAAAATCTAAAATACT
TTTCCGAATTCAAAAACTTGAAACGGATGAACACTTCGGAGATTGTAAACCTATCGGTGACGGAATTAGTGAGATGAGAA
TTAATTATGCTAAAGGCTACCGACTATATTTTAAAGAAAAAGACAACAAAATCGTAATCCTTTTAATTGGTGGAGATAAA
GCAAGTCAACAAAAGGACATAGAGAAAGCGAAAAAAATCTGGAACAGAATAAAAAATGATTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226275 WP_078275235.1 NZ_CP087823:833114-833356 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226275 NZ_CP122379:3188245-3188529 [Aequorivita sp. Ant34-E75]
ATGGAAACCACTAAATTTGACATAGCGGACTATTTGGACAGCGAAGACATGATTGCTGAATATCTCAATACAGTTCTCGA
AGATGGAGACAGTGCTGATTTGATAGTAGCGATCGGGCATATTGCAAAGTCAATCGGAATGACCAAAATTGCGGAGAAAA
CTGGAATGAGCAGACCAAGTCTATACAAAGCATTATCCGATGGGGCGAAACCACAATTTGGAACAATAATGAAGGTGCTG
AAAGCCATTGGTGGTCAAATCAACGTGAAACCAATATCAGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References