Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1832942..1833519 Replicon chromosome
Accession NZ_CP087821
Organism Moraxella bovis strain SAM102604

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP102_RS08830 Protein ID WP_078275234.1
Coordinates 1832942..1833277 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP102_RS08835 Protein ID WP_078275235.1
Coordinates 1833277..1833519 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP102_RS08810 (LP102_08735) 1828642..1829226 + 585 WP_264684517.1 hypothetical protein -
LP102_RS08815 (LP102_08740) 1829391..1831535 + 2145 WP_264678021.1 cation-translocating P-type ATPase -
LP102_RS08820 (LP102_08745) 1831625..1831861 - 237 WP_264678020.1 hypothetical protein -
LP102_RS08825 (LP102_08750) 1831885..1832880 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP102_RS08830 (LP102_08755) 1832942..1833277 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP102_RS08835 (LP102_08760) 1833277..1833519 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP102_RS08840 (LP102_08765) 1833726..1834805 + 1080 WP_264678019.1 3-deoxy-7-phosphoheptulonate synthase -
LP102_RS08845 (LP102_08770) 1835145..1835757 + 613 Protein_1722 IS607 family transposase -
LP102_RS08850 (LP102_08775) 1835841..1835973 + 133 Protein_1723 transposase -
LP102_RS08855 (LP102_08780) 1835970..1836929 + 960 WP_264683651.1 transposase -
LP102_RS08860 (LP102_08785) 1837177..1837899 - 723 WP_264678018.1 tRNA pseudouridine(65) synthase TruC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226270 WP_078275234.1 NZ_CP087821:c1833277-1832942 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226270 NZ_CP122328:3176436-3176651 [Pantoea agglomerans pv. betae]
ATGAACAAAACCCTGACTAAAACCGATTATTTGATGCGACTGCGGCGCTGCCGCTCTCTTGATACCCTGGAAAGGGTGAT
TGAAAAAAATAAGTATGAATTACCGGAAGATGAATTAGCGGTATTTTACTCAGCAGCTGACCATCGCCTGGCGGAACTGA
CGATGAACAAGCTCTACGATAAAGTCCCGGGTTCAGTATGGAAATTTGTCCGTTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226270 WP_078275235.1 NZ_CP087821:c1833519-1833277 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226270 NZ_CP122328:3176034-3176411 [Pantoea agglomerans pv. betae]
ATGGACGAATACTCACCGAAACGGCATGATATTGCCCAGCTTAAATACCTTTGTGAGAGTCTGTTTGACGACAGCATGGC
AACATTAACCGACAGCCATCATGGCTGGGTTAATGATCCCACTTCTGAAAGCAATCTACAGCTTAACGATTTGATTGAGC
ATATCGCCTCTTTCACTATGAATTACAAAATTAAGCACGTTGAAGATGAAGCGCTGATTTCGCAAATCGATGAATATCTT
GATGATACTTTTATGCTATTCAGCAATTATGGTGTCAATAGTCCGGATCTTCAGCGGTGGCAACGTTCAGCAAAACGCTT
ATTTAATCTGTTCACTGAAGAGTGCGCTTTTCTCCAGCAACCGAGCCATTCATTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References