Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 637431..637974 Replicon chromosome
Accession NZ_CP087821
Organism Moraxella bovis strain SAM102604

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag LP102_RS03055 Protein ID WP_245952240.1
Coordinates 637747..637974 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag LP102_RS03050 Protein ID WP_078273964.1
Coordinates 637431..637766 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP102_RS03025 (LP102_02995) 632590..633672 - 1083 WP_264677155.1 tRNA pseudouridine(13) synthase TruD -
LP102_RS03030 (LP102_03000) 633776..634210 - 435 WP_264677154.1 carbonic anhydrase family protein -
LP102_RS03035 (LP102_03005) 634222..634572 - 351 WP_264677153.1 hypothetical protein -
LP102_RS03040 (LP102_03010) 635219..636400 - 1182 WP_264678410.1 fatty acid desaturase -
LP102_RS03045 (LP102_03015) 636663..637247 + 585 Protein_581 TetR/AcrR family transcriptional regulator -
LP102_RS03050 (LP102_03020) 637431..637766 - 336 WP_078273964.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
LP102_RS03055 (LP102_03025) 637747..637974 - 228 WP_245952240.1 hypothetical protein Toxin
LP102_RS03060 (LP102_03030) 638206..638914 + 709 Protein_584 ParA family protein -
LP102_RS03065 (LP102_03035) 639004..640389 - 1386 WP_078273966.1 APC family permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Uncharacterised protein family HicB

(54-104)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8451.18 Da        Isoelectric Point: 4.5519

>T226267 WP_245952240.1 NZ_CP087821:c637974-637747 [Moraxella bovis]
ISERAGSRMAVALNGQVMVFHRPHPSPNTDKSAVMSIRKWLDGMGITPLDDDSQTDEYADKQTDEQEQTHEHNDN

Download         Length: 228 bp

>T226267 NZ_CP122328:642178-642432 [Pantoea agglomerans pv. betae]
ATGAACAAACGACACCAGAAAACGCTGTCAGATGTGTTCGCCCGGCCGGTTAGCGGTTCGATAAAGTGGAGTGATATTGA
ATCTCTTTTTATCGCTCTCGGTGCGGAGGTTCACGAAAGGGAAGGTTCAAGGATTGCGGTACTGCTGAAAGGGCAAAAGA
AAATCTTTCACAGGCCGCACCCCAGACCAACCACTGACAAGGGGGCGGTTAACTCCATCCGGGTATGGCTCGATAGCTTA
GGAATCAGACCATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12189.67 Da        Isoelectric Point: 4.5658

>AT226267 WP_078273964.1 NZ_CP087821:c637766-637431 [Moraxella bovis]
MNTMTINNHKALITFDSELGLFRGEFIGLNGGADFYADSVDGLNEQGALSLQAFLDVCQEQGISPYQSYSGKFVTRLPKE
LHQKIAETATAKGISLNQWINETLSREVGFA

Download         Length: 336 bp

>AT226267 NZ_CP122328:642429-642770 [Pantoea agglomerans pv. betae]
ATGAACAATACACTTAAAATCGACGGCCATCTGGCCGTCATCACCTTTGACCCTGAGATCGAAATGTTTCGCGGGGAGTT
TGTCGGCCTGAACGGCGGTGCTGACTTTTACGCTTACAGCGTCGAGGAGCTGAAAAAAGAGGGTTCAACTTCACTGGCAG
TGTTTCTTGATGAATGCCGCAAAGATGATATTGAACCTTATAAGACATTTAGCGGTAAGGTAACTACCCGCCTGACGCCA
GAACGGCATCAGGCGCTGGCCGTTACTGCTCAAGCACATGGTGTTTCTATTAATGAGTTGCTAAATGAAGGCGTAGATTT
AGTAATTGAAAAACTGTCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References