Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 359920..360572 Replicon chromosome
Accession NZ_CP087821
Organism Moraxella bovis strain SAM102604

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LP102_RS01655 Protein ID WP_264677325.1
Coordinates 360180..360572 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LP102_RS01650 Protein ID WP_264675982.1
Coordinates 359920..360183 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP102_RS01610 (LP102_01580) 354999..355202 + 204 WP_115368689.1 hypothetical protein -
LP102_RS01615 (LP102_01585) 355322..356656 + 1335 WP_264677331.1 deoxyguanosinetriphosphate triphosphohydrolase -
LP102_RS01620 (LP102_01590) 356800..357093 + 294 WP_264677330.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
LP102_RS01625 (LP102_01595) 357086..357358 + 273 WP_228157760.1 type II toxin-antitoxin system YafQ family toxin -
LP102_RS01630 (LP102_01600) 357423..357878 - 456 WP_264677329.1 type IV secretion protein Rhs -
LP102_RS01635 (LP102_01605) 357938..358207 + 270 WP_264677328.1 hypothetical protein -
LP102_RS01640 (LP102_01610) 358204..358584 + 381 WP_264677327.1 type II toxin-antitoxin system VapC family toxin -
LP102_RS01645 (LP102_01615) 358581..359840 + 1260 WP_264677326.1 replication-associated recombination protein A -
LP102_RS01650 (LP102_01620) 359920..360183 + 264 WP_264675982.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LP102_RS01655 (LP102_01625) 360180..360572 + 393 WP_264677325.1 type II toxin-antitoxin system VapC family toxin Toxin
LP102_RS01660 (LP102_01630) 360695..361225 + 531 WP_264678418.1 glucose-6-phosphate 1-dehydrogenase family protein -
LP102_RS01665 (LP102_01635) 361222..361788 - 567 WP_078275186.1 hypothetical protein -
LP102_RS01670 (LP102_01640) 361791..362027 - 237 WP_078275185.1 sulfurtransferase TusA -
LP102_RS01675 (LP102_01645) 362024..362482 - 459 WP_264677324.1 acyl-CoA thioesterase -
LP102_RS01680 (LP102_01650) 362561..363583 - 1023 WP_264677323.1 hypothetical protein -
LP102_RS01685 (LP102_01655) 363614..364492 - 879 WP_264677322.1 uroporphyrinogen-III synthase -
LP102_RS01690 (LP102_01660) 364538..365479 - 942 WP_078275181.1 hydroxymethylbilane synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(10-50)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14629.69 Da        Isoelectric Point: 4.7370

>T226266 WP_264677325.1 NZ_CP087821:360180-360572 [Moraxella bovis]
MKYLLDTNAVIAILNASERFLTTLERHKEREIAISSIVLSELYYGAYKSQKTAQNLEKINLLPFEVLQFNSQDADKAGEI
GATLERRGTPIGSYDTLIAGQAIANDLIVITDNVREFLRVDGLQIENWLK

Download         Length: 393 bp

>T226266 NZ_CP122327:113489-113764 [Pantoea agglomerans pv. betae]
ATGCTAACACCGGTACAAGCGAGTGCTTTTAAACGAGATATAAAACGACAGCAAAAACGCGGTAAGGATATGACCAAGCT
GAAGACGTTAATAAAGCTGCTGGTCGAAGAAAAGGAAATTCCGCCAGAGTATGAAGATCACCCTTTACAGGGAGACTGGC
GAGGCTACCGCGATGCGCACATGGAAGGTGACTGGATACTGATTTATAAGGTAGAAGGTACAGATCTCAAACTCGCCAGA
ACCGGAACTCATCAGGAAATTTTCAGCAACTACTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10153.49 Da        Isoelectric Point: 6.3724

>AT226266 WP_264675982.1 NZ_CP087821:359920-360183 [Moraxella bovis]
MRQTATAKLFWTGNSQAVRLPKAFRFEGTEVRIKKQGRQVIIEPAETQDWAWLDKLRAMPKDDSFEEAILEGRQNLKADE
RDWGAFE

Download         Length: 264 bp

>AT226266 NZ_CP122327:113232-113489 [Pantoea agglomerans pv. betae]
ATGAACGCAGATGCAATGGTAAGAGCGCGTATTCCTAAGGATACGAAAGATCGAGCTGTCGCTGCACTGGACAAGATAGG
CCTCAGCACCTCGGACGTTATCCGCCTGGTTATGATGCGCGTCGCTGAAGAAGGCCGTCTGCCTTTTGAGGTTAAGACCC
CTAACTCTGCCACTCGTCGCGCTATGGATGAACTGGAAAACGGTCACGGTAAACGTTTCGAAACTGCTGACGCCCTATTC
GATGATATGGGGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References