Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafQ-RelB |
| Location | 2293254..2293812 | Replicon | chromosome |
| Accession | NZ_CP087817 | ||
| Organism | Moraxella bovis strain SAM109237 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LP109_RS11540 | Protein ID | WP_228157760.1 |
| Coordinates | 2293254..2293526 (-) | Length | 91 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A1S9ZVK6 |
| Locus tag | LP109_RS11545 | Protein ID | WP_029103533.1 |
| Coordinates | 2293519..2293812 (-) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LP109_RS11500 (LP109_11390) | 2288500..2288736 | + | 237 | WP_078275185.1 | sulfurtransferase TusA | - |
| LP109_RS11505 (LP109_11395) | 2288739..2289305 | + | 567 | WP_078275186.1 | hypothetical protein | - |
| LP109_RS11510 (LP109_11400) | 2289302..2289832 | - | 531 | WP_078275187.1 | HI_0552 family protein | - |
| LP109_RS11515 (LP109_11405) | 2289955..2290347 | - | 393 | WP_078275188.1 | type II toxin-antitoxin system VapC family toxin | - |
| LP109_RS11520 (LP109_11410) | 2290344..2290607 | - | 264 | WP_078275189.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| LP109_RS11525 (LP109_11415) | 2290687..2291946 | - | 1260 | WP_078275190.1 | replication-associated recombination protein A | - |
| LP109_RS11530 (LP109_11420) | 2291925..2292698 | - | 774 | WP_078275191.1 | hypothetical protein | - |
| LP109_RS11535 (LP109_11425) | 2292749..2293189 | + | 441 | WP_208624064.1 | type IV secretion protein Rhs | - |
| LP109_RS11540 (LP109_11430) | 2293254..2293526 | - | 273 | WP_228157760.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| LP109_RS11545 (LP109_11435) | 2293519..2293812 | - | 294 | WP_029103533.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LP109_RS11550 (LP109_11440) | 2293956..2295290 | - | 1335 | WP_078275192.1 | deoxyguanosinetriphosphate triphosphohydrolase | - |
| LP109_RS11555 (LP109_11445) | 2295499..2296215 | - | 717 | WP_078275193.1 | hypothetical protein | - |
| LP109_RS11560 (LP109_11450) | 2296236..2296847 | - | 612 | WP_078275194.1 | methyltransferase | - |
| LP109_RS11565 (LP109_11455) | 2296967..2298301 | + | 1335 | WP_078275195.1 | valine--pyruvate transaminase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10415.99 Da Isoelectric Point: 6.9668
>T226262 WP_228157760.1 NZ_CP087817:c2293526-2293254 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG
Download Length: 273 bp
>T226262 NZ_CP122325:c315544-315074 [Pantoea agglomerans pv. betae]
TTGATTCTCTACAGGCTGACCAAGACAAAGTATCTTTCGACAGCCTGGACGGGATTTGGCGCAAAAGAGGCGGGCGGCCG
CTGGAACAGCATCGGCATCTCCATGGTTTATGTTTCTGAAACAGCATCGCTGACTTTGCTGGAAACACTTGTCCATCTGC
ACTCAGCACACATCCTGGACGCGTTCACACTTCTGCGCATCGATGTTCCCGATGCGCTGATTCAGACCGCTGATATCACT
GAGTTGCCTGCAAACTGGGCCGATGAAGACGCACCGGCAGAACTGGCTGACTATGGAGACGCCTGGTGCTCTGCCTGCGA
TGCGGTTGCGTTGCGTGTTCCCAGTGCCCTCTCCCCTGTAGAATATAACTATCTGTTAAATCCTGAACACCCCGATTTCT
TCCGTATAGTTCAACAGGCTGAGGCTATTCCGTTCCGGTTTGATCGTCGGCTGAAAGCGGATCGTAAATAA
TTGATTCTCTACAGGCTGACCAAGACAAAGTATCTTTCGACAGCCTGGACGGGATTTGGCGCAAAAGAGGCGGGCGGCCG
CTGGAACAGCATCGGCATCTCCATGGTTTATGTTTCTGAAACAGCATCGCTGACTTTGCTGGAAACACTTGTCCATCTGC
ACTCAGCACACATCCTGGACGCGTTCACACTTCTGCGCATCGATGTTCCCGATGCGCTGATTCAGACCGCTGATATCACT
GAGTTGCCTGCAAACTGGGCCGATGAAGACGCACCGGCAGAACTGGCTGACTATGGAGACGCCTGGTGCTCTGCCTGCGA
TGCGGTTGCGTTGCGTGTTCCCAGTGCCCTCTCCCCTGTAGAATATAACTATCTGTTAAATCCTGAACACCCCGATTTCT
TCCGTATAGTTCAACAGGCTGAGGCTATTCCGTTCCGGTTTGATCGTCGGCTGAAAGCGGATCGTAAATAA
Antitoxin
Download Length: 98 a.a. Molecular weight: 11068.31 Da Isoelectric Point: 4.7769
>AT226262 WP_029103533.1 NZ_CP087817:c2293812-2293519 [Moraxella bovis]
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG
Download Length: 294 bp
>AT226262 NZ_CP122325:c315984-315541 [Pantoea agglomerans pv. betae]
ATGAAAACATTCAGCTTTTCTGCTAATAAAACCAGGGCGCCACGCTTATGGCAGGCCGCAGGCCTGAACAACGCTGATGG
TGTCGCCCTGCTGGGCCAGATTAATGAAGGCCTTGATGGCAACGTAGCTCACCTGATCGTCAACTGGGCGAAGATTACGC
AAAACGATCTGCGCAAAATGTCCGGTATTCCCTCCACGACGTTCAGCCGGAGCGTGAAAGCGAAATTCAGCGCTGAACAA
AGTGAACGACTGGTACGAATTATCCGTGTCATTGATCGCGCAGTTGAACTGTTCGAAGGTGATAAGGATGAAGCGCAAAA
ATGGTTGAATGAGCCTAACAGGGCGCTGAGCTGGAAAATGCCCGCAGAACTGATGGCGTCTGAAACCGGGGCATACGAGG
TCATGAAATTAATCACGCGCCTGGAGCACGGAGTTTACTCTTGA
ATGAAAACATTCAGCTTTTCTGCTAATAAAACCAGGGCGCCACGCTTATGGCAGGCCGCAGGCCTGAACAACGCTGATGG
TGTCGCCCTGCTGGGCCAGATTAATGAAGGCCTTGATGGCAACGTAGCTCACCTGATCGTCAACTGGGCGAAGATTACGC
AAAACGATCTGCGCAAAATGTCCGGTATTCCCTCCACGACGTTCAGCCGGAGCGTGAAAGCGAAATTCAGCGCTGAACAA
AGTGAACGACTGGTACGAATTATCCGTGTCATTGATCGCGCAGTTGAACTGTTCGAAGGTGATAAGGATGAAGCGCAAAA
ATGGTTGAATGAGCCTAACAGGGCGCTGAGCTGGAAAATGCCCGCAGAACTGATGGCGTCTGAAACCGGGGCATACGAGG
TCATGAAATTAATCACGCGCCTGGAGCACGGAGTTTACTCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|