Detailed information of TA system TA226258

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 1918287..1918864
• Replicon: chromosome
• Accession: NZ_CP087817
• Organism: Moraxella bovis strain SAM109237

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LP109_RS09565
• Protein ID: WP_078275234.1
• Coordinates: 1918287..1918622 (-)
• Length: 112 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LP109_RS09570
• Protein ID: WP_078275235.1
• Coordinates: 1918622..1918864 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LP109_RS09545 (LP109_09455)	1913774..1914475	-	702	WP_078275358.1	IS1 family transposase	-
LP109_RS09550 (LP109_09460)	1914736..1916880	+	2145	WP_078275231.1	cation-translocating P-type ATPase	-
LP109_RS09555 (LP109_09465)	1916970..1917158	-	189	WP_143821748.1	hypothetical protein	-
LP109_RS09560 (LP109_09470)	1917230..1918225	-	996	WP_208624081.1	polyprenyl synthetase family protein	-
LP109_RS09565 (LP109_09475)	1918287..1918622	-	336	WP_078275234.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LP109_RS09570 (LP109_09480)	1918622..1918864	-	243	WP_078275235.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
LP109_RS09575 (LP109_09485)	1919071..1920150	+	1080	WP_029103111.1	3-deoxy-7-phosphoheptulonate synthase	-
LP109_RS09580 (LP109_09490)	1920532..1921254	-	723	WP_078275236.1	tRNA pseudouridine(65) synthase TruC	-
LP109_RS09585 (LP109_09495)	1921443..1922069	+	627	WP_078275237.1	septation protein IspZ	-
LP109_RS09590 (LP109_09500)	1922229..1922534	+	306	WP_078275238.1	YciI family protein	-
LP109_RS09595 (LP109_09505)	1922543..1922965	+	423	WP_078275239.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (8-84)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (2-63)

Sequences

Toxin

Protein

• Length: 112 a.a.
• Molecular weight: 13059.98 Da
• Isoelectric Point: 8.8194

>T226258 WP_078275234.1 NZ_CP087817:c1918622-1918287 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Nucleotide

• Length: 336 bp

>T226258 NZ_CP122321:c558947-558477 [Pantoea agglomerans pv. gypsophilae]
TTGATTCTCTACAGGCTGACCAAGACAAAGTATCTTTCGACAGCCTGGACGGGATTTGGCGCAAAAGAGGCGGGCGGCCG
CTGGAACAGCATCGGCATATCCATGGTTTATGTTTCTGAAACAGCATCGCTGACTTTGCTGGAAACACTGGTCCATCTGC
ACTCAGCACACATCCTGGATGCTTTCACACTTCTGCGCATCGATGTTCCCGATGTGCTGATTCAGACCGCTGATATCACT
GAGTTGCCTGCAAACTGGGCCGATGAAGACGCACCGGCAGAACTGGCTGACTATGGAGACGCCTGGTGCTCTGCCTGCGA
TGCGGTTGCGTTGCGTGTTCCCAGTGCCCTCTCCCCTGTAGAATATAACTATCTGTTAAATCCTGAACATCCCGAGTTCT
TCCGGATAGTTCAACAGGCTGAGGCCATTCCGTTCCGGTTTGATCGTCGGCTGAAACCGGATCGTACATAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9034.47 Da
• Isoelectric Point: 4.7527

>AT226258 WP_078275235.1 NZ_CP087817:c1918864-1918622 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Nucleotide

• Length: 243 bp

>AT226258 NZ_CP122321:c559387-558944 [Pantoea agglomerans pv. gypsophilae]
ATGAAAACATTCAGTTTTTCTGCGAATAAAACCAGGCCGCCACGCTTATGGCAGGTCGCAGGCCTGAACAACGCTGATGG
TGTCGCCCTGCTTGCCCAGATTAATGAAGGCCTTGATGGCAACGTAGCTCACCTGATCGTCAACTGGGCGAAGATTACGC
AAAACGATCTGCGCAAAATGTCCGGTATTCCCTCCACGACGTTCAGCCGAAGCGTCAAAGCGAAATTCAGCGCTGAACAA
AGTGAACGACTGGTACGTATTATCCGTGTCATTGATCGCGCAGTTGAACTGTTCGAAGGTGATAAGGATGAAGCGCTAAA
ATGGTTGAATGAGCCTAACAGGGCGCTGAGCTGGAAAATGCCCGCAGAACTGATGGCGTCTGAAACCGGGGCTTACGAGG
TCATGAAATTAATCACGCGCCTGGAGCACGGAGTTTACTCTTGA