Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1976524..1977101 Replicon chromosome
Accession NZ_CP087811
Organism Moraxella bovis strain SAM57928

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP106_RS09990 Protein ID WP_078275234.1
Coordinates 1976524..1976859 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP106_RS09995 Protein ID WP_078275235.1
Coordinates 1976859..1977101 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP106_RS09965 (LP106_09870) 1971864..1972064 + 201 WP_112741955.1 hypothetical protein -
LP106_RS09970 (LP106_09875) 1972224..1972808 + 585 WP_112741954.1 hypothetical protein -
LP106_RS09975 (LP106_09880) 1972973..1975117 + 2145 WP_264684081.1 cation-translocating P-type ATPase -
LP106_RS09980 (LP106_09885) 1975207..1975395 - 189 WP_143821748.1 hypothetical protein -
LP106_RS09985 (LP106_09890) 1975467..1976462 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP106_RS09990 (LP106_09895) 1976524..1976859 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP106_RS09995 (LP106_09900) 1976859..1977101 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP106_RS10000 (LP106_09905) 1977308..1978387 + 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP106_RS10005 (LP106_09910) 1978769..1979491 - 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP106_RS10010 (LP106_09915) 1979680..1980306 + 627 WP_078275237.1 septation protein IspZ -
LP106_RS10015 (LP106_09920) 1980466..1980771 + 306 WP_078275238.1 YciI family protein -
LP106_RS10020 (LP106_09925) 1980780..1981202 + 423 WP_078275239.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226240 WP_078275234.1 NZ_CP087811:c1976859-1976524 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226240 NZ_CP122319:c3849778-3849584 [Escherichia coli]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226240 WP_078275235.1 NZ_CP087811:c1977101-1976859 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226240 NZ_CP122319:3849407-3849585 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References