Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) AbkB-shpB/BrnT-BrnA
Location 1758128..1758680 Replicon chromosome
Accession NZ_CP087811
Organism Moraxella bovis strain SAM57928

Toxin (Protein)


Gene name AbkB Uniprot ID A0A1T0A7D3
Locus tag LP106_RS08770 Protein ID WP_029102268.1
Coordinates 1758128..1758406 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LP106_RS08775 Protein ID WP_078273473.1
Coordinates 1758393..1758680 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP106_RS08740 (LP106_08660) 1754115..1754891 - 777 WP_264676230.1 nucleotidyltransferase domain-containing protein -
LP106_RS08745 (LP106_08665) 1755003..1755353 + 351 WP_078273468.1 TIGR01244 family sulfur transferase -
LP106_RS08750 (LP106_08670) 1755501..1756016 + 516 WP_115369660.1 hypothetical protein -
LP106_RS08755 (LP106_08675) 1756009..1756299 + 291 WP_264676229.1 hypothetical protein -
LP106_RS08760 (LP106_08680) 1756512..1757177 + 666 WP_078273471.1 PspA/IM30 family protein -
LP106_RS08765 (LP106_08685) 1757377..1758033 + 657 WP_078273472.1 YqiJ family protein -
LP106_RS08770 (LP106_08690) 1758128..1758406 + 279 WP_029102268.1 BrnT family toxin Toxin
LP106_RS08775 (LP106_08695) 1758393..1758680 + 288 WP_078273473.1 BrnA antitoxin family protein Antitoxin
LP106_RS08780 (LP106_08700) 1758690..1760420 + 1731 WP_078273474.1 flotillin domain-containing protein -
LP106_RS08785 1760464..1760589 - 126 WP_264676709.1 hypothetical protein -
LP106_RS08790 (LP106_08705) 1760618..1762117 - 1500 WP_112742120.1 DUF389 domain-containing protein -
LP106_RS08795 (LP106_08710) 1762196..1763245 - 1050 WP_264676228.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-85)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(36-89)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10484.81 Da        Isoelectric Point: 5.1084

>T226238 WP_029102268.1 NZ_CP087811:1758128-1758406 [Moraxella bovis]
MIFEWDDNKNRTNKQKHGVSFESASRIFLDPFLIVTEDTSSDEVRWLGVGSVDGVVILLVVHTHTDTDGTEIIRIISARK
LSRGEIERYGYC

Download         Length: 279 bp

>T226238 NZ_CP122319:c3706860-3706753 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10979.71 Da        Isoelectric Point: 7.0097

>AT226238 WP_078273473.1 NZ_CP087811:1758393-1758680 [Moraxella bovis]
MAIVRKTLDDIKHTPIDKDELAQLQSMSDDSINYDDIPPLTDVQIANLRLYKPIKQQITLRLDSDIVAWLKKDGKGYQTR
ANQLLRQLMLKELTT

Download         Length: 288 bp

>AT226238 NZ_CP122319:3706907-3706973 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1T0A7D3

Antitoxin

Source ID Structure

References