Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1559883..1560372 Replicon chromosome
Accession NZ_CP087811
Organism Moraxella bovis strain SAM57928

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP106_RS07640 Protein ID WP_112742208.1
Coordinates 1559883..1560140 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP106_RS07645 Protein ID WP_228157840.1
Coordinates 1560130..1560372 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP106_RS07625 (LP106_07555) 1555828..1558350 + 2523 WP_112742210.1 alpha/beta hydrolase -
LP106_RS07630 (LP106_07560) 1558446..1559249 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP106_RS07635 (LP106_07565) 1559315..1559824 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP106_RS07640 (LP106_07570) 1559883..1560140 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP106_RS07645 (LP106_07575) 1560130..1560372 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP106_RS07650 (LP106_07580) 1560417..1560581 + 165 WP_162860378.1 hypothetical protein -
LP106_RS07655 (LP106_07585) 1560663..1560950 - 288 WP_078273310.1 DUF1315 family protein -
LP106_RS07660 (LP106_07590) 1561194..1562427 - 1234 Protein_1491 DUF853 family protein -
LP106_RS07665 (LP106_07595) 1562590..1563108 - 519 WP_264676264.1 bestrophin family protein -
LP106_RS07670 (LP106_07600) 1563098..1563310 - 213 WP_264676263.1 bestrophin family protein -
LP106_RS07675 (LP106_07605) 1563307..1564104 - 798 WP_264676262.1 polyphenol oxidase family protein -
LP106_RS07680 (LP106_07610) 1564223..1565272 - 1050 WP_264676261.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226237 WP_112742208.1 NZ_CP087811:c1560140-1559883 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226237 NZ_CP122319:c3706325-3706218 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226237 WP_228157840.1 NZ_CP087811:c1560372-1560130 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226237 NZ_CP122319:3706373-3706439 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References