Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 2183780..2184338 Replicon chromosome
Accession NZ_CP087806
Organism Moraxella bovis strain SAM57939

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP117_RS11095 Protein ID WP_228157760.1
Coordinates 2184066..2184338 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP117_RS11090 Protein ID WP_264688802.1
Coordinates 2183780..2184073 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP117_RS11060 (LP117_10970) 2179486..2180820 - 1335 WP_264688799.1 valine--pyruvate transaminase -
LP117_RS11065 (LP117_10975) 2180940..2181551 + 612 WP_115368690.1 methyltransferase -
LP117_RS11070 (LP117_10980) 2181658..2182008 + 351 WP_181879486.1 PIN domain protein -
LP117_RS11075 (LP117_10985) 2181998..2182201 + 204 WP_115368689.1 hypothetical protein -
LP117_RS11080 (LP117_10990) 2182321..2183394 + 1074 WP_264688800.1 dNTP triphosphohydrolase -
LP117_RS11085 (LP117_10995) 2183421..2183636 + 216 WP_264688801.1 hypothetical protein -
LP117_RS11090 (LP117_11000) 2183780..2184073 + 294 WP_264688802.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP117_RS11095 (LP117_11005) 2184066..2184338 + 273 WP_228157760.1 type II toxin-antitoxin system YafQ family toxin Toxin
LP117_RS11100 (LP117_11010) 2184403..2184858 - 456 WP_264675985.1 type IV secretion protein Rhs -
LP117_RS11105 (LP117_11015) 2184918..2185187 + 270 WP_264677328.1 hypothetical protein -
LP117_RS11110 (LP117_11020) 2185184..2185564 + 381 WP_264688803.1 type II toxin-antitoxin system VapC family toxin -
LP117_RS11115 (LP117_11025) 2185561..2186820 + 1260 WP_264688804.1 replication-associated recombination protein A -
LP117_RS11120 (LP117_11030) 2186900..2187163 + 264 WP_264675982.1 type II toxin-antitoxin system VapB family antitoxin -
LP117_RS11125 (LP117_11035) 2187160..2187552 + 393 WP_264677325.1 type II toxin-antitoxin system VapC family toxin -
LP117_RS11130 (LP117_11040) 2187675..2188205 + 531 WP_078275187.1 HI_0552 family protein -
LP117_RS11135 (LP117_11045) 2188202..2188768 - 567 WP_078275186.1 hypothetical protein -
LP117_RS11140 (LP117_11050) 2188771..2189007 - 237 WP_078275185.1 sulfurtransferase TusA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-88)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10415.99 Da        Isoelectric Point: 6.9668

>T226230 WP_228157760.1 NZ_CP087806:2184066-2184338 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG

Download         Length: 273 bp

>T226230 NZ_CP122319:2248087-2248437 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACACGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11087.36 Da        Isoelectric Point: 4.7815

>AT226230 WP_264688802.1 NZ_CP087806:2183780-2184073 [Moraxella bovis]
MSRTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG

Download         Length: 294 bp

>AT226230 NZ_CP122319:2247842-2248093 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References