Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 699484..699973 Replicon chromosome
Accession NZ_CP087806
Organism Moraxella bovis strain SAM57939

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP117_RS03795 Protein ID WP_112742208.1
Coordinates 699716..699973 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP117_RS03790 Protein ID WP_228157840.1
Coordinates 699484..699726 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP117_RS03755 (LP117_03735) 694580..695629 + 1050 WP_112742206.1 RluA family pseudouridine synthase -
LP117_RS03760 (LP117_03740) 695748..696545 + 798 WP_112742207.1 polyphenol oxidase family protein -
LP117_RS03765 696542..696754 + 213 WP_264676263.1 bestrophin family protein -
LP117_RS03770 (LP117_03745) 696744..697262 + 519 WP_264676264.1 bestrophin family protein -
LP117_RS03775 (LP117_03750) 697425..698662 + 1238 Protein_737 DUF853 family protein -
LP117_RS03780 (LP117_03755) 698906..699193 + 288 WP_078273310.1 DUF1315 family protein -
LP117_RS03785 (LP117_03760) 699275..699439 - 165 WP_162860378.1 hypothetical protein -
LP117_RS03790 (LP117_03765) 699484..699726 + 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP117_RS03795 (LP117_03770) 699716..699973 + 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP117_RS03800 (LP117_03775) 700032..700541 + 510 WP_112742209.1 peptidylprolyl isomerase -
LP117_RS03805 (LP117_03780) 700607..701410 + 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP117_RS03810 (LP117_03785) 701506..704028 - 2523 WP_264688961.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226225 WP_112742208.1 NZ_CP087806:699716-699973 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226225 NZ_CP122319:c971480-971184 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226225 WP_228157840.1 NZ_CP087806:699484-699726 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226225 NZ_CP122319:c971182-970787 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References