Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 299929..300506 Replicon chromosome
Accession NZ_CP087806
Organism Moraxella bovis strain SAM57939

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP117_RS01630 Protein ID WP_078275234.1
Coordinates 300171..300506 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP117_RS01625 Protein ID WP_078275235.1
Coordinates 299929..300171 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP117_RS01600 (LP117_01590) 295828..296250 - 423 WP_078275239.1 hypothetical protein -
LP117_RS01605 (LP117_01595) 296259..296564 - 306 WP_078275238.1 YciI family protein -
LP117_RS01610 (LP117_01600) 296724..297350 - 627 WP_078275237.1 septation protein IspZ -
LP117_RS01615 (LP117_01605) 297539..298261 + 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP117_RS01620 (LP117_01610) 298643..299722 - 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP117_RS01625 (LP117_01615) 299929..300171 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP117_RS01630 (LP117_01620) 300171..300506 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP117_RS01635 (LP117_01625) 300568..301563 + 996 WP_208624081.1 polyprenyl synthetase family protein -
LP117_RS01640 (LP117_01630) 301635..301823 + 189 WP_143821748.1 hypothetical protein -
LP117_RS01645 (LP117_01635) 301913..304057 - 2145 WP_264684206.1 cation-translocating P-type ATPase -
LP117_RS01650 (LP117_01640) 304222..304806 - 585 WP_112741954.1 hypothetical protein -
LP117_RS01655 (LP117_01645) 304966..305166 - 201 WP_112741955.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226222 WP_078275234.1 NZ_CP087806:300171-300506 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226222 NZ_CP122319:580389-580718 [Escherichia coli]
ATGAACACTCTACCTGCTACAATTTCGCAGGCGGCGAAGCCCTGCCTGTCGCCAGTGGCTGTCTGGCAAATGCTACTGAC
ACGCCTGCTGGAACAACACTATGGCCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTTATTAAGGAACATATCG
ATGCTGGTATCACTCTGGCCGATGCAGTCAATTTTCTGGTGGAAAAGTACGAACTGGTACGTATCGATCACAGAGGATTT
TCGTGGCAACAACAGTCTCCATATATTTCCGTAGTAGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTAA
TGTGAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226222 WP_078275235.1 NZ_CP087806:299929-300171 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226222 NZ_CP122319:580051-580368 [Escherichia coli]
ATGAGCAACACCACATGGGGCCTGCAGCGAGATATCACGCCGCGCCTGGGAGCACGTCTGGTGCAGGAGGGCAACCAGCT
GCACTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTTAGTGACGCCGAATGTCCTAAGCTGGATGTGGTATTTCCAC
ATTTTATCAGCCAGATAGAGTCGATGCTGACCACTGGTGAACTGAATCCCCGCCATGCCCAATGCGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACTCTTGGTAGTTGCGGCTACGTATACATCGCTGTTTACCCCACTCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References