Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1434964..1435453 Replicon chromosome
Accession NZ_CP087805
Organism Moraxella bovis strain SAM57942

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP119_RS07335 Protein ID WP_264676856.1
Coordinates 1434964..1435221 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP119_RS07340 Protein ID WP_228157840.1
Coordinates 1435211..1435453 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP119_RS07315 (LP119_07265) 1429992..1430840 + 849 WP_264676852.1 hypothetical protein -
LP119_RS07320 (LP119_07270) 1430943..1433429 + 2487 WP_264684011.1 alpha/beta hydrolase -
LP119_RS07325 (LP119_07275) 1433526..1434329 - 804 WP_264676854.1 UDP-2,3-diacylglucosamine diphosphatase -
LP119_RS07330 (LP119_07280) 1434396..1434905 - 510 WP_264676855.1 peptidylprolyl isomerase -
LP119_RS07335 (LP119_07285) 1434964..1435221 - 258 WP_264676856.1 Txe/YoeB family addiction module toxin Toxin
LP119_RS07340 (LP119_07290) 1435211..1435453 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP119_RS07345 (LP119_07295) 1435498..1435662 + 165 WP_158079593.1 hypothetical protein -
LP119_RS07350 (LP119_07300) 1435744..1436031 - 288 WP_115005096.1 DUF1315 family protein -
LP119_RS07355 (LP119_07305) 1436054..1437001 - 948 WP_264676857.1 DUF853 domain-containing protein -
LP119_RS07360 (LP119_07310) 1436988..1437404 - 417 WP_264676858.1 DUF853 domain-containing protein -
LP119_RS07365 (LP119_07315) 1437317..1437574 - 258 WP_264676404.1 DUF853 domain-containing protein -
LP119_RS07370 (LP119_07320) 1437792..1438199 - 408 WP_264676859.1 bestrophin family protein -
LP119_RS07375 (LP119_07325) 1438189..1438401 - 213 WP_264676860.1 bestrophin family protein -
LP119_RS07380 (LP119_07330) 1438398..1439195 - 798 WP_264676861.1 polyphenol oxidase family protein -
LP119_RS07385 (LP119_07335) 1439314..1440363 - 1050 WP_264676261.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.00 Da        Isoelectric Point: 8.1158

>T226216 WP_264676856.1 NZ_CP087805:c1435221-1434964 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRINDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226216 NZ_CP122318:3845121-3845228 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226216 WP_228157840.1 NZ_CP087805:c1435453-1435211 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226216 NZ_CP122318:c3845072-3845006 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References