Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2017560..2018137 Replicon chromosome
Accession NZ_CP087803
Organism Moraxella bovis strain SAM57947

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP097_RS10380 Protein ID WP_078275234.1
Coordinates 2017560..2017895 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP097_RS10385 Protein ID WP_078275235.1
Coordinates 2017895..2018137 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP097_RS10355 (LP097_10245) 2012900..2013100 + 201 WP_112741955.1 hypothetical protein -
LP097_RS10360 (LP097_10250) 2013260..2013844 + 585 WP_112741954.1 hypothetical protein -
LP097_RS10365 (LP097_10255) 2014009..2016153 + 2145 WP_264684206.1 cation-translocating P-type ATPase -
LP097_RS10370 (LP097_10260) 2016243..2016431 - 189 WP_143821748.1 hypothetical protein -
LP097_RS10375 (LP097_10265) 2016503..2017498 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP097_RS10380 (LP097_10270) 2017560..2017895 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP097_RS10385 (LP097_10275) 2017895..2018137 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP097_RS10390 (LP097_10280) 2018344..2019423 + 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP097_RS10395 (LP097_10285) 2019805..2020527 - 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP097_RS10400 (LP097_10290) 2020716..2021341 + 626 Protein_2033 septation protein IspZ -
LP097_RS10405 (LP097_10295) 2021501..2021806 + 306 WP_078275238.1 YciI family protein -
LP097_RS10410 (LP097_10300) 2021815..2022237 + 423 WP_078275239.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226209 WP_078275234.1 NZ_CP087803:c2017895-2017560 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226209 NZ_CP122318:c2248974-2248696 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATATTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226209 WP_078275235.1 NZ_CP087803:c2018137-2017895 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226209 NZ_CP122318:c2249237-2248977 [Escherichia coli]
ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCAGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCATTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References