Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) AbkB-shpB/BrnT-BrnA
Location 1796606..1797158 Replicon chromosome
Accession NZ_CP087803
Organism Moraxella bovis strain SAM57947

Toxin (Protein)


Gene name AbkB Uniprot ID A0A1T0A7D3
Locus tag LP097_RS09175 Protein ID WP_029102268.1
Coordinates 1796606..1796884 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LP097_RS09180 Protein ID WP_078273473.1
Coordinates 1796871..1797158 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP097_RS09140 (LP097_09025) 1792606..1792962 - 357 WP_264696654.1 nucleotidyltransferase domain-containing protein -
LP097_RS09145 (LP097_09030) 1792935..1793381 - 447 WP_115369662.1 nucleotidyltransferase domain-containing protein -
LP097_RS09150 (LP097_09035) 1793494..1793844 + 351 WP_115369661.1 TIGR01244 family sulfur transferase -
LP097_RS09155 (LP097_09040) 1793992..1794507 + 516 WP_078273469.1 hypothetical protein -
LP097_RS09160 (LP097_09045) 1794608..1794790 + 183 WP_264683628.1 hypothetical protein -
LP097_RS09165 (LP097_09050) 1795003..1795668 + 666 WP_115369658.1 PspA/IM30 family protein -
LP097_RS09170 (LP097_09055) 1795868..1796524 + 657 WP_264688937.1 YqiJ family protein -
LP097_RS09175 (LP097_09060) 1796606..1796884 + 279 WP_029102268.1 BrnT family toxin Toxin
LP097_RS09180 (LP097_09065) 1796871..1797158 + 288 WP_078273473.1 BrnA antitoxin family protein Antitoxin
LP097_RS09185 (LP097_09070) 1797168..1798898 + 1731 WP_078273474.1 flotillin domain-containing protein -
LP097_RS09190 (LP097_09075) 1799096..1800130 - 1035 WP_264696655.1 DUF389 domain-containing protein -
LP097_RS09195 (LP097_09080) 1800391..1800615 - 225 WP_264696656.1 hypothetical protein -
LP097_RS09200 (LP097_09085) 1800694..1801743 - 1050 WP_264688935.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-85)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(36-89)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10484.81 Da        Isoelectric Point: 5.1084

>T226207 WP_029102268.1 NZ_CP087803:1796606-1796884 [Moraxella bovis]
MIFEWDDNKNRTNKQKHGVSFESASRIFLDPFLIVTEDTSSDEVRWLGVGSVDGVVILLVVHTHTDTDGTEIIRIISARK
LSRGEIERYGYC

Download         Length: 279 bp

>T226207 NZ_CP122318:1643706-1643813 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10979.71 Da        Isoelectric Point: 7.0097

>AT226207 WP_078273473.1 NZ_CP087803:1796871-1797158 [Moraxella bovis]
MAIVRKTLDDIKHTPIDKDELAQLQSMSDDSINYDDIPPLTDVQIANLRLYKPIKQQITLRLDSDIVAWLKKDGKGYQTR
ANQLLRQLMLKELTT

Download         Length: 288 bp

>AT226207 NZ_CP122318:c1643659-1643593 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1T0A7D3

Antitoxin

Source ID Structure

References